Khalid A El Sayed
Overview
Explore the profile of Khalid A El Sayed including associated specialties, affiliations and a list of published articles.
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Articles
108
Citations
1382
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Recent Articles
1.
Tarun M, Elsayed H, Ebrahim H, El Sayed K
Nutrients
. 2025 Feb;
17(3).
PMID: 39940255
: Colorectal cancer (CRC) is the third most common cancer in the US and the second leading cancer-associated mortality cause. Available CRC therapies achieve modest outcomes and fail to prevent...
2.
Shams S, Dawud D, Michalak K, Makhlouf M, Moustafa A, Jazwinski S, et al.
Am J Cancer Res
. 2025 Jan;
14(12):5697-5716.
PMID: 39803655
Prostate cancer (PCa) is the second leading cause of cancer-related deaths among American men. The development of metastatic castration resistant PCa (mCRPC) is the current clinical challenge. Antiandrogens such as...
3.
Mahmud M, Siddique A, Tajmim A, King J, El Sayed K
Molecules
. 2025 Jan;
30(1.
PMID: 39795195
Melanoma is among the most abundant malignancies in the US and worldwide. Ligstroside aglycone (LA) is a rare extra-virgin olive oil-derived monophenolic secoiridoid with diverse bioactivities. LA dose-response screening at...
4.
Mudhish E, Ebrahim H, Helal I, Alhowiriny A, El Sayed K
ACS Pharmacol Transl Sci
. 2024 Dec;
7(12):3902-3913.
PMID: 39698265
Metastatic castration-resistant prostate cancer (mCRPC) is an aggressive phenotype of prostate cancer (PC). Tryptophan oxidative catabolism by indoleamine 2,3-dioxygenase-1 (IDO1) cleaves the indole ring to kynurenine (Kyn), an endogenous ligand...
5.
Al Rihani S, Elfakhri K, Ebrahim H, Al-Ghraiybah N, Alkhalifa A, El Sayed K, et al.
ACS Chem Neurosci
. 2024 Aug;
15(17):3152-3167.
PMID: 39145537
Preclinical and clinical studies have indicated that compromised blood-brain barrier (BBB) function contributes to Alzheimer's disease (AD) pathology. BBB breakdown ranged from mild disruption of tight junctions (TJs) with increased...
6.
Abdelwahed K, Siddique A, Ebrahim H, Qusa M, Mudhish E, Rad A, et al.
Mar Drugs
. 2023 Apr;
21(4).
PMID: 37103355
Metastatic castration-resistant prostate cancer (mCRPC) cells can de novo biosynthesize their own cholesterol and overexpress proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 proved to contribute to mCRPC cell motility since...
7.
Qusa M, Abdelwahed K, Hill R, El Sayed K
Nutrients
. 2023 Feb;
15(3).
PMID: 36771326
Compelling evidence points to the critical role of bioactive extra-virgin olive oil (EVOO) phenolics and gut microbiota (GM) interplay, but reliable models for studying the consequences thereof remain to be...
8.
McGehee O, Ebrahim H, Rad A, Abdelwahed K, Mudhish E, King J, et al.
Molecules
. 2023 Feb;
28(3).
PMID: 36771126
The proprotein convertase subtilisin kexin type 9 (PCSK9) emerged as a molecular target of great interest for the management of cardiovascular disorders due to its ability to reduce low density...
9.
Gaballah M, Ali H, A Hassan Z, Mahgoub S, Ali H, Rhim J, et al.
Am J Cancer Res
. 2022 Sep;
12(8):4015-4027.
PMID: 36119841
Early diagnosis and treatment of patients with aggressive prostate cancer (PCa) remains a clinically unmet need. We aimed to determine the levels of small extracellular vesicle (sEV)-associated microRNAs (miRs); miR-4737,...
10.
Siddique A, Ebrahim H, Tajmim A, King J, Abdelwahed K, Abd Elmageed Z, et al.
Cancers (Basel)
. 2022 Jul;
14(14).
PMID: 35884603
Metastatic castration-resistant prostate cancer (mCRPC) is the most aggressive prostate cancer (PC) phenotype. Cellular lysine methylation is driven by protein lysine methyltransferases (PKMTs), such as those in the SET- and...