Kevin W Plaxco
Overview
Explore the profile of Kevin W Plaxco including associated specialties, affiliations and a list of published articles.
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Articles
210
Citations
5343
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Recent Articles
1.
Bakestani R, Wu Y, Glahn-Martinez B, Kippin T, Plaxco K, Kolkman R
ACS Appl Mater Interfaces
. 2025 Jan;
17(5):8706-8714.
PMID: 39841926
Electrochemical aptamer-based (EAB) sensors are a molecular measurement platform that enables the continuous, real-time measurement of a wide range of drugs and biomarkers in situ in the living body. EAB...
2.
Jeon B, Guareschi M, Stewart J, Wu E, Gopinath A, Arroyo-Curras N, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(1):e2311279121.
PMID: 39793064
The diversity and heterogeneity of biomarkers has made the development of general methods for single-step quantification of analytes difficult. For individual biomarkers, electrochemical methods that detect a conformational change in...
3.
Fetter L, McDonough M, Kippin T, Plaxco K
ACS Sens
. 2024 Nov;
9(12):6675-6684.
PMID: 39570094
Electrochemical aptamer-based (EAB) sensors are the first technology supporting high-frequency, real-time, in vivo molecular measurements that is independent of the chemical reactivity of its targets, rendering it easily generalizable. As...
4.
Yang Y, Gao X, Widdicombe B, Zhang X, Zielinski J, Cheng T, et al.
ACS Nano
. 2024 Sep;
PMID: 39255458
The availability of high-frequency, real-time measurements of the concentrations of specific metabolites in cell culture systems will enable a deeper understanding of cellular metabolism and facilitate the application of good...
5.
Chung J, Billante A, Flatebo C, Leung K, Gerson J, Emmons N, et al.
Sens Diagn
. 2024 Jun;
3(6):1044-1050.
PMID: 38882472
The electrochemical aptamer-based (EAB) sensor platform is the only molecular monitoring approach yet reported that is (1) real time and effectively continuous, (2) selective enough to deploy in the living...
6.
Gerson J, Erdal M, Dauphin-Ducharme P, Idili A, Hespanha J, Plaxco K, et al.
Br J Pharmacol
. 2024 Jun;
181(20):3869-3885.
PMID: 38877797
Background And Purpose: The ability to measure specific molecules at multiple sites within the body simultaneously, and with a time resolution of seconds, could greatly advance our understanding of drug...
7.
Verrinder E, Gerson J, Leung K, Kippin T, Plaxco K
ACS Sens
. 2024 May;
9(6):3205-3211.
PMID: 38775190
Electrochemical aptamer-based (EAB) sensors represent the first molecular measurement technology that is both (1) independent of the chemical reactivity of the target, and thus generalizable to many targets and (2)...
8.
Wu Y, Shi J, Kippin T, Plaxco K
Langmuir
. 2024 Apr;
40(16):8703-8710.
PMID: 38616608
Electrochemical aptamer-based (EAB) sensors, a minimally invasive means of performing high-frequency, real-time measurement of drugs and biomarkers in situ in the body, have traditionally been fabricated by depositing their target-recognizing...
9.
Leung K, Gerson J, Emmons N, Heemstra J, Kippin T, Plaxco K
Angew Chem Int Ed Engl
. 2024 Mar;
63(21):e202316678.
PMID: 38500260
Electrochemical aptamer-based sensors support the high-frequency, real-time monitoring of molecules-of-interest in vivo. Achieving this requires methods for correcting the sensor drift seen during in vivo placements. While this correction ensures...
10.
Alkhamis O, Canoura J, Wu Y, Emmons N, Wang Y, Honeywell K, et al.
J Am Chem Soc
. 2024 Jan;
146(5):3230-3240.
PMID: 38277259
The ability to quantify cocaine in biological fluids is crucial for both the diagnosis of intoxication and overdose in the clinic as well as investigation of the drug's pharmacological and...