Kevin M Lawrence
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Explore the profile of Kevin M Lawrence including associated specialties, affiliations and a list of published articles.
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15
Citations
299
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Recent Articles
11.
Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway
Chanalaris A, Lawrence K, Townsend P, Davidson S, Jamshidi Y, Jashmidi Y, et al.
Biochem Biophys Res Commun
. 2005 Feb;
328(2):442-8.
PMID: 15694367
The UCN homologues SCP and SRP bind specifically to the CRFR2 receptor, whereas UCN binds to both CRFR1 and CRFR2. We have previously demonstrated that all three peptides are cardioprotective,...
12.
Taylor P, McConnell J, Khan I, Holemans K, Lawrence K, Asare-Anane H, et al.
Am J Physiol Regul Integr Comp Physiol
. 2004 Sep;
288(1):R134-9.
PMID: 15388492
We previously reported that prenatal and suckling exposure to a maternal diet rich in animal fat leads to cardiovascular dysfunction in young adult rat offspring with subsequent development of dyslipidemia...
13.
Lawrence K, Townsend P, Davidson S, Carroll C, Eaton S, Hubank M, et al.
Biochem Biophys Res Commun
. 2004 Sep;
321(2):479-86.
PMID: 15358201
We have previously shown, using Affymetrix gene chip technology, that urocortin induces the expression of several diverse genes in cardiac myocytes. An ATP sensitive inwardly rectifying potassium channel, Katp (Kir6.1),...
14.
Townsend P, Cutress R, Carroll C, Lawrence K, Scarabelli T, Packham G, et al.
J Biol Chem
. 2004 Feb;
279(20):20723-8.
PMID: 14978028
BAG-1 (Bcl-2-associated athanogene-1) proteins interact with the HSC70 and HSP70 heat shock proteins and have been proposed to promote cell survival by coordinating the function of these chaperones with the...
15.
Janjua S, Lawrence K, Ng L, Latchman D
Cardiovasc Toxicol
. 2003 Oct;
3(3):255-62.
PMID: 14555790
The corticotrophin-releasing hormone-related factor, urocortin (Ucn) and the interleukin (IL)-6 family cytokine cardiotrophin-1 (CT-1) are both cardioprotective agents able to protect the heart from ischemic damage. In both cases the...