Kevin M Lawrence
Overview
Explore the profile of Kevin M Lawrence including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
299
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Recent Articles
1.
Jones R, Lawrence K, Higgins S, Richardson S, Townsend P
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563508
Post-traumatic OA (PTOA) is often triggered by injurious, high-impact loading events which result in rapid, excessive chondrocyte cell death and a phenotypic shift in residual cells toward a more catabolic...
2.
Fuller K, Lawrence K, Ross J, Grabowska U, Shiroo M, Samuelsson B, et al.
Bone
. 2021 Jan;
145:115354.
PMID: 33461907
No abstract available.
3.
Owens G, Lawrence K, Jackson T, Crosbie E, Sayan B, Kitchener H, et al.
Cancer Med
. 2017 Jan;
6(2):408-415.
PMID: 28109061
Urocortin (UCN1) peptide shares structural and functional homology with corticotropin-releasing factor (CRF). UCN1 is significantly reduced in endometrial adenocarcinoma compared to healthy controls. However, there are no data which evaluate...
4.
Stenbeck G, Lawrence K, Albert A
Front Endocrinol (Lausanne)
. 2012 Sep;
3:103.
PMID: 22936925
A precise control of vesicular trafficking is crucial not only for osteoclastic bone resorption, but also for the crosstalk between osteoclasts and osteoblasts, which regulates bone homeostasis. In addition to...
5.
Combs C, Fuller K, Kumar H, Albert A, Pirianov G, McCormick J, et al.
J Endocrinol
. 2011 Nov;
212(2):187-97.
PMID: 22083217
This study investigated the role of urocortin (UCN), a member of the corticotrophin-releasing factor (CRF) family of peptides, in osteoclast maturation and function. We found that 10(-7) M UCN significantly...
6.
Barry S, Lawrence K, McCormick J, Soond S, Hubank M, Eaton S, et al.
J Mol Endocrinol
. 2010 May;
45(2):69-85.
PMID: 20501665
The urocortin (UCN) hormones UCN1 and UCN2 have been shown previously to confer significant protection against myocardial ischaemia/reperfusion (I/R) injury; however, the molecular mechanisms underlying their action are poorly understood....
7.
Fuller K, Lawrence K, Ross J, Grabowska U, Shiroo M, Samuelsson B, et al.
Bone
. 2007 Oct;
42(1):200-11.
PMID: 17962093
The coupling between bone formation and resorption creates a therapeutic impasse in osteoporosis: antiresorptive therapy halts bone loss, but also inhibits bone formation, and therefore does not cure the condition....
8.
McCormick J, Barry S, Sivarajah A, Stefanutti G, Townsend P, Lawrence K, et al.
FASEB J
. 2006 Aug;
20(12):2115-7.
PMID: 16935931
The signal transducer and activator of transcription (STAT) family are latent transcription factors involved in a variety of signal transduction pathways, including cell death cascades. STAT1 has been shown to...
9.
Collino M, Patel N, Lawrence K, Collin M, Latchman D, Yaqoob M, et al.
Kidney Int
. 2005 Jul;
68(2):529-36.
PMID: 16014029
Background: We have recently reported that pretreatment of rats with endotoxin (lipopolysaccharide, LPS) and selective agonists of the nuclear receptor peroxisome proliferator-activated receptor-gamma (PPARgamma) protect the kidney against ischemia/reperfusion (I/R)...
10.
Townsend P, Cragg M, Davidson S, McCormick J, Barry S, Lawrence K, et al.
J Cell Sci
. 2005 Mar;
118(Pt 8):1629-39.
PMID: 15784679
STAT-1 plays a role in mediating stress responses to various stimuli and has also been implied to be a tumour suppressor. Here, we report that STAT-1-deficient cells have defects both...