Kevin Leguay
Overview
Explore the profile of Kevin Leguay including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
17
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Recent Articles
1.
Leguay K, Kent O
Onco Targets Ther
. 2025 Jan;
18:147-159.
PMID: 39882405
The gene is nearly ubiquitously subjected to activating mutation in pancreatic adenocarcinomas (PDAC), occurring at a frequency of over 90% in tumors. Mutant KRAS drives sustained signaling through the MAPK...
2.
Leguay K, Decelle B, Elkholi I, Bouvier M, Cote J, Carreno S
J Cell Biol
. 2022 Apr;
221(6).
PMID: 35482006
At mitotic entry, reorganization of the actomyosin cortex prompts cells to round-up. Proteins of the ezrin, radixin, and moesin family (ERM) play essential roles in this process by linking actomyosin...
3.
Leguay K, Decelle B, He Y, Pagniez A, Hogue M, Kobayashi H, et al.
J Cell Sci
. 2021 Mar;
134(7).
PMID: 33712451
Ezrin, radixin and moesin compose the family of ERM proteins. They link actin filaments and microtubules to the plasma membrane to control signaling and cell morphogenesis. Importantly, their activity promotes...
4.
De Jamblinne C, Decelle B, Dehghani M, Joseph M, Sriskandarajah N, Leguay K, et al.
J Cell Biol
. 2020 Sep;
219(11).
PMID: 32960945
Proteins of the ezrin, radixin, and moesin (ERM) family control cell and tissue morphogenesis. We previously reported that moesin, the only ERM in Drosophila, controls mitotic morphogenesis and epithelial integrity....