Kevin Jouvin
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Explore the profile of Kevin Jouvin including associated specialties, affiliations and a list of published articles.
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13
Citations
178
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Recent Articles
1.
Matcha K, Chernichenko K, Jouvin K, Guduguntla S, Tran D, Bell S, et al.
J Org Chem
. 2022 Aug;
87(16):10736-10746.
PMID: 35921209
A palladium-catalyzed Heck reaction between 2-oxyacrylates and aryl bromides was developed, where DavePhos was a unique ligand that efficiently promoted the reaction. The products, 2-oxycinnamates, served as excellent precursors, providing...
2.
Metayer B, Angeli A, Mingot A, Jouvin K, Evano G, Supuran C, et al.
J Enzyme Inhib Med Chem
. 2018 May;
33(1):804-808.
PMID: 29706097
After hydrofluorination of ynesulphonamides in superacid or in the presence of hydrofluoric acid/base reagents, a series of α-fluoroenamides has been synthesised and tested for the inhibition of carbonic anhydrase (CA,...
3.
Preindl J, Jouvin K, Laurich D, Seidel G, Furstner A
Chemistry
. 2015 Nov;
22(1):237-47.
PMID: 26594016
3-Oxo-5-alkynoic acid esters, on treatment with a carbophilic catalyst, undergo 6-endo-dig cyclization reactions to furnish either 2-pyrones or 4-pyrones in high yields. The regiochemical course can be dialed in by...
4.
Jouvin K, Matheis C, Goossen L
Chemistry
. 2015 Sep;
21(41):14324-7.
PMID: 26332514
An AlCl3 -catalyzed CH thiocyanation was discovered and combined with a Langlois-type trifluoromethylation to afford aryl trifluoromethyl thioethers directly from arenes, N-thiocyanatosuccinimide (NTS) and Ruppert-Prakash reagent. An analogous combination with...
5.
Bayarmagnai B, Matheis C, Jouvin K, Goossen L
Angew Chem Int Ed Engl
. 2015 Mar;
54(19):5753-6.
PMID: 25766315
A copper-CF2 H complex generated in situ from copper thiocyanate and TMSCF2 H smoothly converts organothiocyanates into valuable difluoromethyl thioethers. This reaction step can be combined with several thiocyanation methods...
6.
Metayer B, Compain G, Jouvin K, Martin-Mingot A, Bachmann C, Marrot J, et al.
J Org Chem
. 2015 Jan;
80(7):3397-410.
PMID: 25569215
(E)- and (Z)-α-fluoroenamides could be easily prepared with high levels of chemo- and regioselectivities by hydrofluorination of readily available ynamides with HF/pyridine. The scope and limitations of this new process...
7.
Matheis C, Jouvin K, Goossen L
Org Lett
. 2014 Nov;
16(22):5984-7.
PMID: 25380504
A Sandmeyer-type difluoromethylation process has been developed that allows the straightforward conversion of (hetero-)arenediazonium salts into the corresponding difluoromethyl (hetero-)arenes under mild conditions. The actual difluoromethylating reagent, a difluoromethyl-copper complex,...
8.
Jouvin K, Veillard R, Theunissen C, Alayrac C, Gaumont A, Evano G
Org Lett
. 2013 Aug;
15(17):4592-5.
PMID: 23980522
An original and user-friendly synthesis of alkynylphosphine-boranes, useful building blocks in organic synthesis, based on an oxidative P-alkynylation reaction with readily available copper acetylides is reported. The ability of a...
9.
Stereoselective hydrofluorination of ynamides: a straightforward synthesis of novel α-fluoroenamides
Compain G, Jouvin K, Martin-Mingot A, Evano G, Marrot J, Thibaudeau S
Chem Commun (Camb)
. 2012 Apr;
48(42):5196-8.
PMID: 22514037
α-Fluoroenamides, potent rigid fluorinated bioisosters of ureas, have been synthesized by a highly regio- and stereo-selective hydrofluorination of ynamides in anhydrous HF. This reaction provides the first general entry to...
10.
Jouvin K, Bayle A, Legrand F, Evano G
Org Lett
. 2012 Mar;
14(6):1652-5.
PMID: 22397691
An efficient and general copper-catalyzed method is reported for the synthesis of phenol-derived 1-bromoenol ethers, ynol ethers, and ketene acetals by chemodivergent copper-catalyzed cross-coupling between readily available 1,1-dibromo-1-alkenes and phenols.