Kenneth J Serio
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Explore the profile of Kenneth J Serio including associated specialties, affiliations and a list of published articles.
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11
Citations
109
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Recent Articles
1.
Mao J, Xue B, Smoake J, Lu Q, Park H, Henning S, et al.
J Nutr Biochem
. 2016 Jun;
34:118-25.
PMID: 27289489
Oncomirs are microRNAs (miRNA) associated with carcinogenesis and malignant transformation. They have emerged as potential molecular targets for anti-cancer therapy. We hypothesize that grape seed procyanidin extract (GSE) exerts antineoplastic...
2.
Mao J, Nie W, Tsu I, Jin Y, Rao J, Lu Q, et al.
Cancer Prev Res (Phila)
. 2010 Jul;
3(9):1132-40.
PMID: 20668019
Emerging preclinical data suggests that tea possess anticarcinogenic and antimutagenic properties. We therefore hypothesize that white tea extract (WTE) is capable of favorably modulating apoptosis, a mechanism associated with lung...
3.
Mao J, Tashkin D, Tsu I, Serio K
Cancer Prev Res (Phila)
. 2009 Jan;
1(4):266-74.
PMID: 19138970
Leukotrienes have been implicated to play a prominent inductive role in carcinogenesis. We previously reported that bronchoalveolar lavage (BAL) cells from smokers manifested higher levels of leukotriene B4 (LTB4) production...
4.
Serio K, Luo C, Luo L, Mao J
Am J Physiol Lung Cell Mol Physiol
. 2006 Sep;
292(1):L215-22.
PMID: 16980379
We studied the effect of tumor necrosis factor (TNF)-alpha exposure on cysteinyl leukotriene (LT) synthesis by cells of monocyte/macrophage lineage. TNF-alpha conditioning of monocytic THP-1 cells and primary human monocytes...
5.
Serio K, Reddy K, Bigby T
Am J Physiol Cell Physiol
. 2004 Dec;
288(5):C1125-33.
PMID: 15625306
We examined induced expression of the 5-lipoxygenase-activating protein (FLAP), which is critical for leukotriene synthesis in mononuclear phagocytes. Prolonged exposure to the bacterial component, lipopolysaccharide (LPS), increased FLAP gene transcription,...
6.
Mao J, Tsu I, Dubinett S, Adams B, Sarafian T, Baratelli F, et al.
Clin Cancer Res
. 2004 Oct;
10(20):6872-8.
PMID: 15501964
Purpose: Emerging data continue to link carcinogenesis to inflammatory events involving the eicosanoid metabolic pathways. We therefore evaluated the effects of cyclooxygenase (COX)-2 inhibition on leukotriene (LT) B(4) synthesis in...
7.
Mao J, Roth M, Serio K, Baratelli F, Zhu L, Holmes E, et al.
Clin Cancer Res
. 2003 Dec;
9(16 Pt 1):5835-41.
PMID: 14676104
Purpose: Preclinical data suggest that the cyclooxygenase (COX)-2/prostaglandin (PG) E2 signaling pathway plays an essential role in conferring the malignant phenotype in non-small cell lung cancer. We hypothesized that treatment...
8.
Serio K, Hodulik C, Bigby T
Adv Exp Med Biol
. 2003 Apr;
507:61-6.
PMID: 12664565
No abstract available.
9.
Serio K, Johns S, Luo L, Hodulik C, Bigby T
Chest
. 2003 Mar;
123(3 Suppl):426S.
PMID: 12629014
No abstract available.
10.
Serio K, Johns S, Luo L, Hodulik C, Bigby T
J Immunol
. 2003 Feb;
170(4):2121-8.
PMID: 12574384
We studied the effects of LPS on cysteinyl leukotriene (LT) synthesis and LTC(4) synthase expression in mononuclear phagocytes. Conditioning of the monocyte-like cell line, THP-1, with LPS for 7 days...