Kenneth G Macleod
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Explore the profile of Kenneth G Macleod including associated specialties, affiliations and a list of published articles.
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24
Citations
589
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Recent Articles
1.
Kuntic M, Kuntic I, Krishnankutty R, Gericke A, Oelze M, Junglas T, et al.
Redox Biol
. 2022 Dec;
59:102580.
PMID: 36566737
Worldwide, up to 8.8 million excess deaths/year have been attributed to air pollution, mainly due to the exposure to fine particulate matter (PM). Traffic-related noise is an additional contributor to...
2.
Judd E, Tierney J, Huber B, Wing S, Lunt D, Ford H, et al.
Sci Data
. 2022 Dec;
9(1):753.
PMID: 36473868
Paleotemperature proxy data form the cornerstone of paleoclimate research and are integral to understanding the evolution of the Earth system across the Phanerozoic Eon. Here, we present PhanSST, a database...
3.
Petrizzo M, Amaglio G, Watkins D, Macleod K, Huber B, Hasegawa T, et al.
Paleoceanogr Paleoclimatol
. 2022 Oct;
37(9):e2022PA004474.
PMID: 36247808
Oceanic Anoxic Event 2, spanning the Cenomanian/Turonian boundary (93.9 Ma), was an episode of major perturbations in the global carbon cycle. To investigate the response of biota and the paleoceanographic...
4.
Petrizzo M, Macleod K, Watkins D, Wolfgring E, Huber B
Paleoceanogr Paleoclimatol
. 2022 Aug;
37(1):e2021PA004353.
PMID: 35910494
The latest Cenomanian to Santonian sedimentary record recovered at IODP Expedition 369 Site U1513 in the Mentelle Basin (SE Indian Ocean, paleolatitude 60°S at 85 Ma) is studied to interpret...
5.
Moore K, Cerqueira V, Macleod K, Mullen P, Hayward R, Green S, et al.
Explor Target Antitumor Ther
. 2022 Apr;
3:97-116.
PMID: 35441158
Aim: A model of progressively endocrine-resistant breast cancer was investigated to identify changes that can occur in signaling pathways after endocrine manipulation. Methods: The MCF7 breast cancer model is sensitive...
6.
Bolado-Carrancio A, Lee M, Ewing A, Muir M, Macleod K, Gallagher W, et al.
Oncogene
. 2021 Sep;
40(44):6235-6247.
PMID: 34556814
ISG15 is an ubiquitin-like modifier that is associated with reduced survival rates in breast cancer patients. The mechanism by which ISG15 achieves this however remains elusive. We demonstrate that modification...
7.
Temps C, Lietha D, Webb E, Li X, Dawson J, Muir M, et al.
Cancer Res
. 2021 Aug;
81(21):5438-5450.
PMID: 34417202
Despite the approval of several multikinase inhibitors that target SRC and the overwhelming evidence of the role of SRC in the progression and resistance mechanisms of many solid malignancies, inhibition...
8.
Madsen R, Longden J, Knox R, Robin X, Vollmy F, Macleod K, et al.
Dis Model Mech
. 2021 Jan;
14(3).
PMID: 33514588
Activating PIK3CA mutations are known 'drivers' of human cancer and developmental overgrowth syndromes. We recently demonstrated that the 'hotspot' PIK3CAH1047R variant exerts unexpected allele dose-dependent effects on stemness in human...
9.
Byron A, Bernhardt S, Ouine B, Cartier A, Macleod K, Carragher N, et al.
Sci Rep
. 2020 Dec;
10(1):21985.
PMID: 33319783
Reverse-phase protein array (RPPA) technology uses panels of high-specificity antibodies to measure proteins and protein post-translational modifications in cells and tissues. The approach offers sensitive and precise quantification of large...
10.
Punovuori K, Migueles R, Malaguti M, Blin G, Macleod K, Carragher N, et al.
Development
. 2019 Oct;
146(21).
PMID: 31601548
A switch from E- to N-cadherin regulates the transition from pluripotency to neural identity, but the mechanism by which cadherins regulate differentiation was previously unknown. Here, we show that the...