Kenichi Yakushijin
Overview
Explore the profile of Kenichi Yakushijin including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
302
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Recent Articles
1.
Wu Z, Li L, Liu S, Yakushijin F, Yakushijin K, Horne D, et al.
J Nucl Med
. 2014 May;
55(7):1178-84.
PMID: 24854793
Unlabelled: Accumulating evidence suggests that neurotensin receptors (NTRs) play key roles in cancer growth and survival. In this study, we developed a simple and efficient method to radiolabel neurotensin peptide...
2.
Tian Y, Nam S, Liu L, Yakushijin F, Yakushijin K, Buettner R, et al.
PLoS One
. 2012 Nov;
7(11):e49306.
PMID: 23166634
Melanoma is generally refractory to current chemotherapy, thus new treatment strategies are needed. In this study, we synthesized a series of spirooxindole derivatives (SOID-1 to SOID-12) and evaluated their antitumor...
3.
Buettner R, Corzano R, Rashid R, Lin J, Senthil M, Hedvat M, et al.
ACS Chem Biol
. 2011 Jan;
6(5):432-43.
PMID: 21226522
Stat3 is a latent transcription factor that promotes cell survival and proliferation and is often constitutively active in multiple cancers. Inhibition of Stat3 signaling pathways suppresses cell survival signals and...
4.
Ma Y, Nam S, Jove R, Yakushijin K, Horne D
Bioorg Med Chem Lett
. 2009 Dec;
20(1):83-6.
PMID: 19948404
A series of ageladine A analogs that include 2-aminoimidazo[4,5-c]azepines (seven-membered rings) and 2-amino-3H-imidazo[4,5-c]pyridine (six-membered rings) derivatives were synthesized and evaluated for their anticancer effects against several human cancer cell lines...
5.
Miyake F, Yakushijin K, Horne D
Angew Chem Int Ed Engl
. 2005 Apr;
44(21):3280-2.
PMID: 15861446
No abstract available.
6.
Miyake F, Yakushijin K, Horne D
Org Lett
. 2004 Nov;
6(23):4249-51.
PMID: 15524455
The preparation of two new synthons, 2,5- and 2,6-dibromotryptophan esters, and their use in diastereoselective intramolecular N-acyliminium ion spirocyclization methodology for the rapid construction of spirotryprostatin A and analogues are...
7.
Miyake F, Yakushijin K, Horne D
Angew Chem Int Ed Engl
. 2004 Oct;
43(40):5357-60.
PMID: 15468070
No abstract available.
8.
Castedo M, Perfettini J, Roumier T, Valent A, Raslova H, Yakushijin K, et al.
Oncogene
. 2004 Mar;
23(25):4362-70.
PMID: 15048075
A conflict in cell cycle progression or DNA damage can lead to mitotic catastrophe when the DNA structure checkpoints are inactivated, for instance when the checkpoint kinase Chk2 is inhibited....
9.
Castedo M, Perfettini J, Roumier T, Yakushijin K, Horne D, Medema R, et al.
Oncogene
. 2004 Mar;
23(25):4353-61.
PMID: 15048074
Fusion between nonsynchronized cells leads to the formation of heterokarya which transiently activate Cyclin-dependent kinase 1 (Cdk1)/cyclin B1 and enter the prophase of the cell cycle, where they arrest due...
10.
Preparation and synthetic applications of 2-halotryptamines: synthesis of elacomine and isoelacomine
Miyake F, Yakushijin K, Horne D
Org Lett
. 2004 Feb;
6(5):711-3.
PMID: 14986956
The preparation of 2-halotryptamines from tryptamine is described. New stereoselective intramolecular iminium ion spirocyclization methodology for the construction of spiro[pyrrolidine-3,3'-oxindoles] is outlined in synthetic studies of elacomine (1) and isoelacomine...