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Kelly McDaniel

Explore the profile of Kelly McDaniel including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 733
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Recent Articles
1.
McDaniel K, Wu N, Zhou T, Huang L, Sato K, Venter J, et al.
Hepatology . 2019 Feb; 69(6):2562-2578. PMID: 30723922
Cholangiopathies are diseases that affect cholangiocytes, the cells lining the biliary tract. Liver stem cells (LSCs) are able to differentiate into all cells of the liver and possibly influence the...
2.
Pei Y, Li H, Cai Y, Zhou J, Luo X, Ma L, et al.
J Endocrinol . 2018 Nov; 239(3):365-376. PMID: 30400017
Adenosine 2A receptor (A2AR) exerts anti-inflammatory effects. However, the role of A2AR in obesity-associated adipose tissue inflammation remains to be elucidated. The present study examined the expression of A2AR in...
3.
Luo X, Li H, Ma L, Zhou J, Guo X, Woo S, et al.
Gastroenterology . 2018 Sep; 155(6):1971-1984.e4. PMID: 30213555
Background & Aims: Transmembrane protein 173 (TMEM173 or STING) signaling by macrophage activates the type I interferon-mediated innate immune response. The innate immune response contributes to hepatic steatosis and non-alcoholic...
4.
Wu N, McDaniel K, Zhou T, Ramos-Lorenzo S, Wu C, Huang L, et al.
Am J Physiol Gastrointest Liver Physiol . 2018 Jun; 315(3):G385-G398. PMID: 29848019
microRNA-21 (miRNA) is one of the most abundant miRNAs in chronic liver injuries including alcoholic liver injury. Previous studies have demonstrated that miR-21 plays a role in inflammation in the...
5.
Wan Y, McDaniel K, Wu N, Ramos-Lorenzo S, Glaser T, Venter J, et al.
Am J Pathol . 2017 Nov; 187(12):2788-2798. PMID: 29128099
Alcoholic liver disease remains a major cause of liver-related morbidity and mortality, which ranges from alcoholic steatohepatitis to fibrosis/cirrhosis and hepatocellular carcinoma, and the related mechanisms are understood poorly. In...
6.
McDaniel K, Huang L, Sato K, Wu N, Annable T, Zhou T, et al.
J Biol Chem . 2017 May; 292(27):11336-11347. PMID: 28536261
The let-7/Lin28 axis is associated with the regulation of key cellular regulatory genes known as microRNAs in various human disorders and cancer development. This study evaluated the role of the...
7.
Kyritsi K, Meng F, Zhou T, Wu N, Venter J, Francis H, et al.
Am J Pathol . 2017 May; 187(7):1551-1565. PMID: 28502477
Hepatic fibrosis occurs during the progression of primary sclerosing cholangitis (PSC) and is characterized by accumulation of extracellular matrix proteins. Proliferating cholangiocytes and activated hepatic stellate cells (HSCs) participate in...
8.
McDaniel K, Meng F, Wu N, Sato K, Venter J, Bernuzzi F, et al.
Hepatology . 2016 Sep; 65(2):544-559. PMID: 27639079
Conclusion: The definitive endoderm marker and the positive regulator of biliary development, FoxA2, mediates the therapeutic effect of biliary-committed progenitor cells during cholestatic liver injury. (Hepatology 2017;65:544-559).
9.
McDaniel K, Hall C, Sato K, Lairmore T, Marzioni M, Glaser S, et al.
Am J Physiol Gastrointest Liver Physiol . 2016 Mar; 310(10):G757-65. PMID: 27012771
The diagnosis and treatment of liver disease remain a major health concern worldwide because of the diverse etiologies of this disease. For this reason, new therapeutic targets are greatly needed...
10.
Wan Y, Garner J, Wu N, Phillip L, Han Y, McDaniel K, et al.
J Cell Mol Med . 2015 Dec; 20(2):195-203. PMID: 26645107
Diabetes mellitus is one of the most severe endocrine metabolic disorders in the world that has serious medical consequences with substantial impacts on the quality of life. Type 2 diabetes...