Paolo Onori
Overview
Explore the profile of Paolo Onori including associated specialties, affiliations and a list of published articles.
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Articles
126
Citations
3280
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Recent Articles
1.
Casini A, Vivacqua G, Ceci L, Leone S, Vaccaro R, Tagliafierro M, et al.
Cell Tissue Res
. 2024 Dec;
399(2):247-265.
PMID: 39656240
Alpha-synuclein (α-syn) is widely expressed in presynaptic neuron terminals, and its structural alterations play an important role in the pathogenesis of Parkinson's disease (PD). Aggregated α-syn has been found in...
2.
Vivacqua G, Mancinelli R, Leone S, Vaccaro R, Garro L, Carotti S, et al.
Neurogastroenterol Motil
. 2024 Mar;
36(5):e14780.
PMID: 38462652
Background: Different studies have shown the key role of endoplasmic reticulum (ER) stress in autoimmune and chronic inflammatory disorders, as well as in neurodegenerative diseases. ER stress leads to the...
3.
Casini A, Vivacqua G, Vaccaro R, Renzi A, Leone S, Pannarale L, et al.
Eur J Histochem
. 2023 Oct;
67(4).
PMID: 37859350
Cholangiocytes, the epithelial cells that line the biliary tree, can proliferate under the stimulation of several factors through both autocrine and paracrine pathways. The cocaine-amphetamine-regulated-transcript (CART) peptide has several physiological...
4.
Owen T, Carpino G, Chen L, Kundu D, Wills P, Ekser B, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Jun;
16(4):513-540.
PMID: 37336290
Background & Aims: Primary sclerosing cholangitis (PSC) leads to ductular reaction and fibrosis and is complicated by vascular dysfunction. Cholangiocyte and endothelial cell crosstalk modulates their proliferation in cholestatic models....
5.
Kundu D, Kennedy L, Zhou T, Ekser B, Meadows V, Sybenga A, et al.
Hepatology
. 2023 Feb;
78(1):243-257.
PMID: 36799449
Background And Aims: NAFLD is characterized by steatosis, hepatic inflammation, and fibrosis, which can develop into NASH. Patients with NAFLD/NASH have increased ductular reaction (DR) and biliary senescence. High fat/high...
6.
Wu N, Zhou T, Carpino G, Baiocchi L, Kyritsi K, Kennedy L, et al.
Hepatology
. 2023 Feb;
77(6):1849-1865.
PMID: 36799446
Background And Aims: Secretin (SCT) and secretin receptor (SR, only expressed on cholangiocytes within the liver) play key roles in modulating liver phenotypes. Forkhead box A2 (FoxA2) is required for...
7.
Kyritsi K, Wu N, Zhou T, Carpino G, Baiocchi L, Kennedy L, et al.
Cell Biosci
. 2023 Jan;
13(1):5.
PMID: 36624475
Background: Alcohol-related liver disease (ALD) is characterized by ductular reaction (DR), liver inflammation, steatosis, fibrosis, and cirrhosis. The secretin (Sct)/secretin receptor (SR) axis (expressed only by cholangiocytes) regulates liver phenotypes...
8.
Casini A, Leone S, Vaccaro R, Vivacqua G, Ceci L, Pannarale L, et al.
Life (Basel)
. 2022 Dec;
12(12).
PMID: 36556493
Liver cancer represents a global health challenge with worldwide growth. Hepatocellular carcinoma (HCC) is the most common type of liver cancer. Indeed, approximately 90% of HCC cases have a low...
9.
Meadows V, Marakovits C, Ekser B, Kundu D, Zhou T, Kyritsi K, et al.
Am J Physiol Gastrointest Liver Physiol
. 2022 Nov;
324(1):G60-G77.
PMID: 36410025
Primary sclerosing cholangitis (PSC) is characterized by increased ductular reaction (DR), liver fibrosis, hepatic total bile acid (TBA) levels, and mast cell (MC) infiltration. Apical sodium BA transporter (ASBT) expression...
10.
Overi D, Carpino G, Cristoferi L, Onori P, Kennedy L, Francis H, et al.
JHEP Rep
. 2022 Oct;
4(11):100556.
PMID: 36267871
Background & Aims: Primary biliary cholangitis (PBC) is a chronic cholangiopathy characterised by immuno-mediated injury of interlobular bile ducts leading to intrahepatic cholestasis and progressive liver fibrosis. PBC histology is...