Keith James
Overview
Explore the profile of Keith James including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
2963
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Recent Articles
11.
Chouhan G, James K
Org Lett
. 2011 Apr;
13(10):2754-7.
PMID: 21526759
A range of multivalent heteroaryl ligands, copper sources, and solvent systems have been investigated for use in CuAAC-mediated macrocyclization reactions. These studies have revealed the key factors governing selectivity for...
12.
Bogdan A, James K
Chemistry
. 2010 Nov;
16(48):14506-12.
PMID: 21038332
A series of 12- to 22-membered macrocycles, with druglike functionality and properties, have been generated by using a simple and efficient copper-catalyzed azide-acetylene cycloaddition reaction, conducted in flow in high-temperature...
13.
Dhami P, Saffrey P, Bruce A, Dillon S, Chiang K, Bonhoure N, et al.
PLoS One
. 2010 Sep;
5(8):e12339.
PMID: 20808788
It has recently been shown that nucleosome distribution, histone modifications and RNA polymerase II (Pol II) occupancy show preferential association with exons ("exon-intron marking"), linking chromatin structure and function to...
14.
Meyer F, Liras S, Guzman-Perez A, Perreault C, Bian J, James K
Org Lett
. 2010 Aug;
12(17):3870-3.
PMID: 20695449
Functionalized alpha-amino acid building blocks have been prepared in good yield with high regiocontrol and preservation of stereochemistry via iridium-catalyzed borylation of suitably protected aromatic alpha-amino acid derivatives. The utility...
15.
James K
J Occup Health Psychol
. 2008 Jan;
13(1):24-31.
PMID: 18211166
Hazardous-material trucking has recently been identified as an area of high potential risk for terrorism. Some recent theory and case study papers have argued for the importance of collective efficacy...
16.
Rada-Iglesias A, Wallerman O, Koch C, Ameur A, Enroth S, Clelland G, et al.
Hum Mol Genet
. 2005 Oct;
14(22):3435-47.
PMID: 16221759
We present a detailed in vivo characterization of hepatocyte transcriptional regulation in HepG2 cells, using chromatin immunoprecipitation and detection on PCR fragment-based genomic tiling path arrays covering the encyclopedia of...
17.
Hall N, Karras M, Raine J, Carlton J, Kooij T, Berriman M, et al.
Science
. 2005 Jan;
307(5706):82-6.
PMID: 15637271
Plasmodium berghei and Plasmodium chabaudi are widely used model malaria species. Comparison of their genomes, integrated with proteomic and microarray data, with the genomes of Plasmodium falciparum and Plasmodium yoelii...
18.
Young S, Murphy M, Zhu X, Harnden P, ODonnell M, James K, et al.
Int J Cancer
. 2004 Sep;
112(4):653-60.
PMID: 15382047
Intravesical administration of live M. bovis BCG organisms for carcinoma in situ of the urinary bladder is the most successful immunotherapy for solid malignancy. Nevertheless BCG-therapy is associated with significant...
19.
Wain J, Diem Nga L, Kidgell C, James K, Fortune S, Song Diep T, et al.
Antimicrob Agents Chemother
. 2003 Aug;
47(9):2732-9.
PMID: 12936967
The first outbreak of multidrug-resistant (MDR) typhoid fever in Vietnam was in 1993, and by 1995 nearly 90% of cases were MDR. Plasmid HCM1, sequenced in full, is an incHI1...
20.
Parkhill J, Sebaihia M, Preston A, Murphy L, Thomson N, Harris D, et al.
Nat Genet
. 2003 Aug;
35(1):32-40.
PMID: 12910271
Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative beta-proteobacteria that colonize the respiratory tracts of mammals. B. pertussis is a strict human pathogen of recent evolutionary origin...