Kei Haniuda
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Explore the profile of Kei Haniuda including associated specialties, affiliations and a list of published articles.
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20
Citations
400
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Recent Articles
1.
Higashiyama M, Haniuda K, Nihei Y, Kazuno S, Kikkawa M, Miura Y, et al.
Life Sci Alliance
. 2024 Feb;
7(4).
PMID: 38331476
IgA nephropathy (IgAN) is caused by deposition of IgA in the glomerular mesangium. The mechanism of selective deposition and production of IgA is unclear; however, we recently identified the involvement...
2.
Koshida K, Ito M, Yakabe K, Takahashi Y, Tai Y, Akasako R, et al.
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37239894
Foxp3 regulatory T (Treg) cells prevent excessive immune responses against dietary antigens and commensal bacteria in the intestine. Moreover, Treg cells contribute to the establishment of a symbiotic relationship between...
3.
Nihei Y, Higashiyama M, Miyauchi K, Haniuda K, Suzuki Y, Kubo M, et al.
Int Immunol
. 2023 May;
35(8):377-386.
PMID: 37140172
Immunoglobulin A (IgA) is the most abundant isotype of antibodies and provides a first line of defense at the mucosa against pathogens invading the host. It has been widely accepted...
4.
Nihei Y, Haniuda K, Higashiyama M, Asami S, Iwasaki H, Fukao Y, et al.
Sci Adv
. 2023 Mar;
9(12):eadd6734.
PMID: 36947618
Immunoglobulin A (IgA) nephropathy (IgAN) is the most common type of primary glomerulonephritis, often progressing to renal failure. IgAN is triggered by IgA deposition in the glomerular mesangium by an...
5.
Amano S, Haniuda K, Fukao S, Aoki H, Ueha S, Kitamura D
J Immunol
. 2023 Mar;
210(7):959-972.
PMID: 36883865
IgE Abs are a common mediator of allergic responses and are generally produced in type 2 immune responses to allergens. Allergen stimulation of IgE-bound FcεRI on mast cells or basophils...
6.
Kato K, Haniuda K, Fukao S, Kitamura D
Int Immunol
. 2023 Jan;
35(6):275-286.
PMID: 36689362
T cell independent type II (TI-II) antigens, such as capsular polysaccharides, have multivalent epitopes, which induce B cell activation, plasma cell differentiation and antibody production by strongly cross-linking B cell...
7.
Li C, Ward L, Nguyen A, Lam E, Dasoveanu D, Ahmed M, et al.
Mucosal Immunol
. 2022 Feb;
15(3):418-427.
PMID: 35181738
Although eosinophils are important contributors to mucosal immune responses, mechanisms that regulate their accumulation in mucosal-associated lymphoid tissues remain ill-defined. Combining bone marrow chimeras and pharmacological inhibition approaches, here we...
8.
Fukao S, Haniuda K, Tamaki H, Kitamura D
Elife
. 2021 Oct;
10.
PMID: 34693907
Antigens (Ags) with multivalent and repetitive structure elicit IgG production in a T-cell-independent manner. However, the mechanisms by which such T-cell-independent type-2 (TI-2) Ags induce IgG responses remain obscure. Here,...
9.
Haniuda K, Gommerman J, Reich H
Semin Immunopathol
. 2021 Oct;
43(5):649-656.
PMID: 34664087
The immunopathogenic mechanisms underlying immunoglobulin A nephropathy (IgAN) are poorly understood, yet it is one of the most common causes of kidney failure globally. The commonly referenced syndrome of synpharyngitic...
10.
Takatsuka S, Yamada H, Haniuda K, Ichihashi M, Chiba J, Kitamura D
Bio Protoc
. 2021 Mar;
9(4):e3174.
PMID: 33654980
Membrane proteins such as cytokine receptors and G protein-coupled receptors can be drug targets. Recently, we have generated specific monoclonal antibodies (mAbs) against the mouse IL-9 receptor (IL-9R) and found...