Keh-Yang Wang
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Explore the profile of Keh-Yang Wang including associated specialties, affiliations and a list of published articles.
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7
Citations
166
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Recent Articles
1.
Wang J, Hung C, Liou Y, Liu C, Yeh K, Wang K, et al.
Elife
. 2024 May;
12.
PMID: 38752723
A causal relationship exists among the aging process, organ decay and disfunction, and the occurrence of various diseases including cancer. A genetically engineered mouse model, termed or (K74R), carrying mutation...
2.
Hung C, Wang K, Liou Y, Wang J, Huang A, Lee T, et al.
Int J Mol Sci
. 2020 Nov;
21(22).
PMID: 33182781
Erythroid Krüppel-like factor (EKLF/KLF1) was identified initially as a critical erythroid-specific transcription factor and was later found to be also expressed in other types of hematopoietic cells, including megakaryocytes and...
3.
Wang K, Chen C, Tsai S, Shen C
Sci Rep
. 2016 Nov;
6:37490.
PMID: 27886214
DNA methylation at C of CpG dyads (CpG) in vertebrate genomes is essential for gene regulation, genome stability and development. We show in this study that proper functioning of post-replicative...
4.
Wang K, Chen C, Shen C
Epigenomics
. 2014 Aug;
6(3):353-63.
PMID: 25111488
Vertebrate DNA methyltransferases (DNMTs) have been thought to primarily function to covalently add a methyl group to the 5-position of cytosine. However, recent discovery of the DNA demethylation and dehydroxymethylation...
5.
Chen C, Wang K, Shen C
J Biol Chem
. 2013 Feb;
288(13):9084-91.
PMID: 23393137
Methylation at the 5-position of DNA cytosine on the vertebrate genomes is accomplished by the combined catalytic actions of three DNA methyltransferases (DNMTs), the de novo enzymes DNMT3A and DNMT3B...
6.
Chen C, Wang K, Shen C
J Biol Chem
. 2012 Aug;
287(40):33116-21.
PMID: 22898819
For cytosine (C) demethylation of vertebrate DNA, it is known that the TET proteins could convert 5-methyl C (5-mC) to 5-hydroxymethyl C (5-hmC). However, DNA dehydroxymethylase(s), or enzymes able to...
7.
Wang K, Shen C
Oncogene
. 2004 Sep;
23(47):7898-902.
PMID: 15378011
We have examined the relationship between DNA mismatch repair and deficiency of DNA methylation in a mouse embryonic cell line, Dnmt1-/- ES, with homologous deletion of the gene coding for...