Chen-Hsin Albert Yu
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Explore the profile of Chen-Hsin Albert Yu including associated specialties, affiliations and a list of published articles.
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8
Citations
50
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0
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Recent Articles
1.
Huang A, Su J, Hung Y, Chiang H, Chen Y, Huang Y, et al.
BMC Genomics
. 2024 Jun;
25(1):600.
PMID: 38877417
Background: Splicing variants are a major class of pathogenic mutations, with their severity equivalent to nonsense mutations. However, redundant and degenerate splicing signals hinder functional assessments of sequence variations within...
2.
Wang J, Hung C, Liou Y, Liu C, Yeh K, Wang K, et al.
Elife
. 2024 May;
12.
PMID: 38752723
A causal relationship exists among the aging process, organ decay and disfunction, and the occurrence of various diseases including cancer. A genetically engineered mouse model, termed or (K74R), carrying mutation...
3.
Murashko O, Yeh K, Yu C, Kaberdin V, Lin-Chao S
Microbiol Spectr
. 2023 Mar;
:e0415822.
PMID: 36939343
Although fluoride-containing compounds are widely used to inhibit bacterial growth, the reprogramming of gene expression underlying cellular responses to fluoride, especially under anaerobic conditions, is still poorly understood. Here, we...
4.
Kulkarni R, Kasani S, Tsai C, Tung S, Yeh K, Yu C, et al.
Life Sci Alliance
. 2023 Jan;
6(4).
PMID: 36717248
FAM21 (family with sequence similarity 21) is a component of the Wiskott-Aldrich syndrome protein and SCAR homologue (WASH) protein complex that mediates actin polymerization at endosomal membranes to facilitate sorting...
5.
Wang C, Chen T, Tan G, Chang F, Sridharan S, Yu C, et al.
Cancer Res
. 2022 Nov;
83(2):251-263.
PMID: 36354374
Significance: Degradation of p53 mediated by MEX3A drives ovarian cancer growth by circumventing p53 tumor suppressive functions, suggesting targeting MEX3A as a potential strategy for treating of ovarian cancer expressing...
6.
Chiang H, Chen Y, Su J, Lin H, Yu C, Hung Y, et al.
Nat Struct Mol Biol
. 2022 Oct;
29(11):1043-1055.
PMID: 36303034
It is estimated that 10%-30% of disease-associated genetic variants affect splicing. Splicing variants may generate deleteriously altered gene product and are potential therapeutic targets. However, systematic diagnosis or prediction of...
7.
Copper Availability Influences the Transcriptomic Response of Candida albicans to Fluconazole Stress
Hunsaker E, Yu C, Franz K
G3 (Bethesda)
. 2021 Mar;
11(4).
PMID: 33693623
The ability of pathogens to maintain homeostatic levels of essential biometals is known to be important for survival and virulence in a host, which itself regulates metal availability as part...
8.
Yan Q, Ahn S, Mba Medie F, Sharma-Kuinkel B, Park L, Scott W, et al.
PLoS One
. 2017 Jun;
12(6):e0179033.
PMID: 28594911
We previously showed that chromosome 8 of A/J mice was associated with susceptibility to S. aureus infection. However, the specific genes responsible for this susceptibility are unknown. Chromosome substitution strain...