Keerthana Krishnan
Overview
Explore the profile of Keerthana Krishnan including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
947
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Recent Articles
1.
Nakano Y, Gamper H, McGuigan H, Maharjan S, Li J, Sun Z, et al.
Nat Commun
. 2025 Jan;
16(1):1047.
PMID: 39865096
While all native tRNAs undergo extensive post-transcriptional modifications as a mechanism to regulate gene expression, mapping these modifications remains challenging. The critical barrier is the difficulty of readthrough of modifications...
2.
Ghosh D, McDonald H, Dutta R, Krishnan K, Thilakan J, Paul M, et al.
Cells
. 2024 Nov;
13(21.
PMID: 39513892
Non-small cell lung cancer (NSCLC) has established predictive biomarkers that enable decisions on treatment regimens for many patients. However, resistance to therapy is widespread. It is therefore essential to have...
3.
Baral T, M S, Thomas L, B R, Krishnan K, Shetty S, et al.
Tuberculosis (Edinb)
. 2024 Jun;
148:102535.
PMID: 38941909
Background: Isoniazid-induced pancreatitis is a potentially serious adverse drug reaction, however, the frequency of its occurrence is unknown. We conducted a systematic review to explore this adverse drug reaction comprehensively....
4.
Nakano Y, Gamper H, McGuigan H, Maharjan S, Sun Z, Krishnan K, et al.
bioRxiv
. 2023 Dec;
PMID: 38106225
Monitoring the dynamic changes of cellular tRNA pools is challenging, due to the extensive post-transcriptional modifications of individual species. The most critical component in tRNAseq is a processive reverse transcriptase...
5.
Wulf M, Maguire S, Dai N, Blondel A, Posfai D, Krishnan K, et al.
Nucleic Acids Res
. 2021 Sep;
50(1):e2.
PMID: 34581823
Template-switching reverse transcription is widely used in RNA sequencing for low-input and low-quality samples, including RNA from single cells or formalin-fixed paraffin-embedded (FFPE) tissues. Previously, we identified the native eukaryotic...
6.
Yost S, Duran-Pinedo A, Krishnan K, Frias-Lopez J
PLoS Pathog
. 2017 Jun;
13(6):e1006457.
PMID: 28632755
Dysbiosis, or the imbalance in the structural and/or functional properties of the microbiome, is at the origin of important infectious inflammatory diseases such as inflammatory bowel disease (IBD) and periodontal...
7.
Mougeot J, Stevens C, Cotton S, Morton D, Krishnan K, Brennan M, et al.
J Oral Microbiol
. 2016 Apr;
8:30379.
PMID: 27065347
Background: Over 700 bacterial species reside in human oral cavity, many of which are associated with local or distant site infections. Extensive characterization of the oral microbiome depends on the...
8.
Yost S, Duran-Pinedo A, Teles R, Krishnan K, Frias-Lopez J
Genome Med
. 2015 Oct;
7(1):111.
PMID: 26507874
No abstract available.
9.
Yost S, Duran-Pinedo A, Teles R, Krishnan K, Frias-Lopez J
Genome Med
. 2015 Apr;
7(1):27.
PMID: 25918553
Background: Periodontitis is a polymicrobial biofilm-induced inflammatory disease that affects 743 million people worldwide. The current model to explain periodontitis progression proposes that changes in the relative abundance of members...
10.
Martin H, Wani S, Steptoe A, Krishnan K, Nones K, Nourbakhsh E, et al.
Genome Biol
. 2014 Mar;
15(3):R51.
PMID: 24629056
Background: MicroRNAs (miRNAs) bind to mRNAs and target them for translational inhibition or transcriptional degradation. It is thought that most miRNA-mRNA interactions involve the seed region at the 5' end...