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Kechun Tang

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Articles 27
Citations 627
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Recent Articles
1.
Chirasani V, Kal S, Biswas N, Mahata S, Tang K, Pasqua T, et al.
bioRxiv . 2025 Jan; PMID: 39803582
Hypertension, a major cause of cardiomyopathy, is one of the most critical risk factors for heart failure and mortality worldwide. Loss of metabolic flexibility of cardiomyocytes is one of the...
2.
Mahata S, Jati S, Munoz-Mayorga D, Shahabi S, Tang K, Tao Y, et al.
Res Sq . 2024 Aug; PMID: 39149499
Metabolic disorders such as insulin resistance and hypertension are potential risk factors for aging and neurodegenerative diseases. These conditions are reversed in Chromogranin A knockout (CgA-KO) mice. This study investigates...
3.
Jati S, Munoz-Mayorga D, Shahabi S, Tang K, Tao Y, Dickson D, et al.
bioRxiv . 2024 Jun; PMID: 38915622
Our previous studies have indicated that insulin resistance, hyperglycemia, and hypertension in aged wild-type (WT) mice can be reversed in mice lacking chromogranin-A (CgA-KO mice). These health conditions are associated...
4.
Liu M, Shahabi S, Jati S, Tang K, Gao H, Jin Z, et al.
Front Endocrinol (Lausanne) . 2022 Nov; 13:1037465. PMID: 36440192
Aims: Aging is associated with the development of insulin resistance and hypertension which may stem from inflammation induced by accumulation of toxic bacterial DNA crossing the gut barrier. The aim...
5.
Nogueira L, Zemljic-Harpf A, Yusufi R, Ranjbar M, Susanto C, Tang K, et al.
Am J Physiol Regul Integr Comp Physiol . 2022 Oct; 323(6):R849-R860. PMID: 36250633
To date, there has been a lag between the rise in E-cigarette use and an understanding of the long-term health effects. Inhalation of E-cigarette aerosol delivers high doses of nicotine,...
6.
Tang K, Mahata S
Methods Mol Biol . 2022 Oct; 2565:331-342. PMID: 36205904
The determination of plasma catecholamine levels is commonly used as a measure of the sympathetic nervous system's response to stress and is highly important for diagnosis, therapy, and prognosis of...
7.
Gao H, Jin Z, Tang K, Ji Y, Suarez J, Suarez J, et al.
J Am Heart Assoc . 2022 Feb; 11(4):e024561. PMID: 35112881
Background Obesity is an established risk factor for hypertension. Although obesity-induced gut barrier breach leads to the leakage of various microbiota-derived products into host circulation and distal organs, the roles...
8.
Gao H, Luo Z, Ji Y, Tang K, Jin Z, Ly C, et al.
Nat Commun . 2022 Jan; 13(1):565. PMID: 35091566
Various microbial products leaked from gut lumen exacerbate tissue inflammation and metabolic disorders in obesity. Vsig4+ macrophages are key players preventing infiltration of bacteria and their products into host tissues....
9.
Bandyopadhyay G, Tang K, Webster N, van den Bogaart G, Mahata S
Acta Physiol (Oxf) . 2022 Jan; 235(1):e13775. PMID: 34985191
Aim: Defects in hepatic glycogen synthesis contribute to post-prandial hyperglycaemia in type 2 diabetic patients. Chromogranin A (CgA) peptide Catestatin (CST: hCgA ) improves glucose tolerance in insulin-resistant mice. Here,...
10.
Ying W, Tang K, Avolio E, Schilling J, Pasqua T, Liu M, et al.
Hypertension . 2021 Apr; 77(5):1670-1682. PMID: 33826401
[Figure: see text].