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Geert van den Bogaart

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Articles 104
Citations 3302
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Recent Articles
1.
Chirasani V, Kal S, Biswas N, Mahata S, Tang K, Pasqua T, et al.
bioRxiv . 2025 Jan; PMID: 39803582
Hypertension, a major cause of cardiomyopathy, is one of the most critical risk factors for heart failure and mortality worldwide. Loss of metabolic flexibility of cardiomyocytes is one of the...
2.
Marhaeny H, Rohmah L, Pratama Y, Kasatu S, Miatmoko A, Addimaysqi R, et al.
PLoS One . 2024 Dec; 19(12):e0315312. PMID: 39729447
Food allergies are a global health problem that continues to grow annually, with a prevalence of more than 10%. Shrimp allergy is the most common and life-threatening allergy. There is...
3.
Kopp J, Jahn D, Vogt G, Psoma A, Ratto E, Morelle W, et al.
Cell Mol Life Sci . 2024 Dec; 82(1):4. PMID: 39680136
Loss-of-function variants in ATP6V0A2, encoding the trans Golgi V-ATPase subunit V0a2, cause wrinkly skin syndrome (WSS), a connective tissue disorder with glycosylation defects and aberrant cortical neuron migration. We used...
4.
de Wit A, Bianchi F, van den Bogaart G
Immunol Cell Biol . 2024 Nov; 103(2):161-177. PMID: 39609891
T cells of the adaptive immune system recognize pathogens and malignantly transformed cells through a process called antigen presentation. During this process, peptides are displayed on major histocompatibility complex (MHC)...
5.
Zhang Y, Sigaeva A, Elias-Llumbet A, Fan S, Woudstra W, de Boer R, et al.
Proc Natl Acad Sci U S A . 2024 Oct; 121(43):e2317921121. PMID: 39401360
Free radical generation plays a key role in many biological processes including cell communication, maturation, and aging. In addition, free radical generation is usually elevated in cells under stress as...
6.
Warner H, Franciosa G, van der Borg G, Coenen B, Faas F, Koenig C, et al.
Cell Rep . 2024 Feb; 43(3):113866. PMID: 38416638
To mount an adaptive immune response, dendritic cells must migrate to lymph nodes to present antigens to T cells. Critical to 3D migration is the nucleus, which is the size-limiting...
7.
Monti M, Milanetti E, Frans M, Miotto M, Di Rienzo L, Baranov M, et al.
J Phys Chem B . 2024 Jan; 128(2):451-464. PMID: 38190651
It is not well understood why severe acute respiratory syndrome (SARS)-CoV-2 spreads much faster than other β-coronaviruses such as SARS-CoV and Middle East respiratory syndrome (MERS)-CoV. In a previous publication,...
8.
Jiang M, Karsenberg R, Bianchi F, van den Bogaart G
Immunol Lett . 2023 Dec; 265:7-15. PMID: 38122906
The membrane protein CD36 is a lipid transporter, scavenger receptor, and receptor for the antiangiogenic protein thrombospondin 1 (TSP1). CD36 is expressed by cancer cells and by many associated cells...
9.
Maassen S, Warner H, Grijpstra P, van den Bogaart G
MethodsX . 2023 Aug; 11:102288. PMID: 37533791
Collagen remodelling is a vital process for embryonic development and homoeostatic maintenance of the adult body. Collagen remodelling is a complex process in fibroblasts, macrophages and other cells, whereby new...
10.
Frans M, Kuipers E, Bianchi F, van den Bogaart G
Immunol Cell Biol . 2023 Jun; 101(8):727-734. PMID: 37332154
The Golgi membrane protein GOLM1/GP73/GOLPH2 has been found to impact cytokine production in both infectious disease and cancer. In viral infections, GOLM1 levels are increased, and this lowers the production...