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Kazuhiro Haraguchi

Explore the profile of Kazuhiro Haraguchi including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 85
Citations 564
Followers 0
Related Specialties
Biochemistry
Chemistry
Gastroenterology
Top 10 Co-Authors
Hiromichi Tanaka
Hiroki Kumamoto
Masanori Baba
Eikichi Ihara
Haruei Ogino
Yung-Chi Cheng
Yutaka Kubota
Yosuke Minoda
Hisashi Shimada
Yoshihiro Ogawa
Published In
J Org Chem
Nucleosides Nucleotides Nucleic Acids
Nucleic Acids Symp Ser (Oxf)
Antimicrob Agents Chemother
Endoscopy
Affiliations
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Recent Articles
11.
Comparison of the procedure time differences between hybrid endoscopic submucosal dissection and conventional endoscopic submucosal dissection in patients with early gastric neoplasms: a study protocol for a multi-center randomized controlled trial...
Esaki M, Ihara E, Fujii H, Sumida Y, Haraguchi K, Takahashi S, et al.
Trials . 2022 Feb; 23(1):166. PMID: 35189939
Background: Endoscopic submucosal dissection (ESD) is widely accepted as a local treatment for gastrointestinal tract tumors. As a simplified endoscopic procedure, hybrid ESD (H-ESD) has been performed for colorectal neoplasms...
12.
4-Thiofuranoid Glycal: Versatile Glycosyl Donor for the Selective Synthesis of β-anomer of 4'-thionucleoside and its Biological Activities
Haraguchi K, Kumamoto H, Tanaka H
Curr Med Chem . 2021 Nov; 29(21):3684-3731. PMID: 34781859
The first highly diastereoselective synthesis of β-anomers of 4'-thionucleosides has been carried out by means of electrophilic glycosidation utilizing 3,5-O-(di-tertbutylsilylene) (DTBS)-4-thiofuranoid glycal as a glycosyl donor. The resulting glycosides were...
13.
Efficacy of hybrid endoscopic submucosal dissection with SOUTEN in gastric lesions: An porcine model basic study
Esaki M, Ihara E, Hashimoto N, Abe S, Aratono C, Shiga N, et al.
World J Gastrointest Surg . 2021 Jul; 13(6):563-573. PMID: 34194614
Background: Hybrid endoscopic submucosal dissection (ESD) that comprises mucosal incision and partial submucosal dissection followed by snaring in a planned manner, has been developed for endoscopic resection of gastrointestinal neoplasms...
14.
Endoscopic mucosal resection endoscopic submucosal dissection for superficial non-ampullary duodenal tumors
Esaki M, Haraguchi K, Akahoshi K, Tomoeda N, Aso A, Itaba S, et al.
World J Gastrointest Oncol . 2020 Sep; 12(8):918-930. PMID: 32879668
Background: The selection of endoscopic treatments for superficial non-ampullary duodenal epithelial tumors (SNADETs) is controversial. Aim: To compare the efficacy and safety of endoscopic mucosal resection (EMR) and endoscopic submucosal...
15.
Superiority of mucosal incision-assisted biopsy over ultrasound-guided fine needle aspiration biopsy in diagnosing small gastric subepithelial lesions: a propensity score matching analysis
Minoda Y, Chinen T, Osoegawa T, Itaba S, Haraguchi K, Akiho H, et al.
BMC Gastroenterol . 2020 Jan; 20(1):19. PMID: 31964357
Background: Gastric subepithelial lesions, including gastrointestinal stromal tumors, are often found during routine gastroscopy. While endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) has been the gold standard for diagnosing gastric subepithelial...
16.
Synthesis and evaluation of the anti-hepatitis B virus activity of 4'-Azido-thymidine analogs and 4'-Azido-2'-deoxy-5-methylcytidine analogs: structural insights for the development of a novel anti-HBV agent
Onitsuka K, Tokuda R, Kuwata-Higashi N, Kumamoto H, Aoki M, Amano M, et al.
Nucleosides Nucleotides Nucleic Acids . 2019 Sep; 39(4):518-529. PMID: 31514570
Hepatitis B virus (HBV) infection is a major worldwide health problem that requires the development of improved antiviral therapies. Here, a series of 4'-Azido-thymidine/4'-Azido-2'-deoxy-5-methylcytidine derivatives (, ) were synthesized, and...
17.
An alternative method for the synthesis of 2'-halogeno-1',2'-unsaturated uridine derivatives through -elimination of pivalic acid of 2'-halogeno- 2'-deoxy-1'-pivaloyloxyuracil nucleoside: preparation of its 2'--branched nucleosides
Haraguchi K, Gen E, Kumamoto H, Itoh Y, Tanaka H
Nucleosides Nucleotides Nucleic Acids . 2019 Aug; 39(1-3):426-438. PMID: 31429364
An alternative method for the preparation of 2'-bromo- () and 2'-iodo- () 1',2'-unsaturated uracil nucleosides has been developed. The protocol was on the basis of the -elimination of pivalic acid...
18.
Objective validity of the Japan Narrow-Band Imaging Expert Team classification system for the differential diagnosis of colorectal polyps
Minoda Y, Ogino H, Chinen T, Ihara E, Haraguchi K, Akiho H, et al.
Dig Endosc . 2019 Mar; 31(5):544-551. PMID: 30861599
Background And Aim: The Japan Narrow-Band Imaging (NBI) Expert Team (JNET) classification is a recently proposed NBI magnifying endoscopy-based classification system for colorectal tumors. Although the usefulness of this system...
19.
Mucosal Profiles of Immune Molecules Related to T Helper and Regulatory T Cells Predict Future Relapse in Patients With Quiescent Ulcerative Colitis
Fukaura K, Iboshi Y, Ogino H, Ihara E, Nakamura K, Nishihara Y, et al.
Inflamm Bowel Dis . 2019 Jan; 25(6):1019-1027. PMID: 30668727
Background: T helper (Th)- and regulatory T (Treg) cell-related immune molecules are implicated in ulcerative colitis (UC). However, the association between their mucosal expression during remission and the subsequent clinical...
20.
Synthesis, Anti-HBV, and Anti-HIV Activities of 3'-Halogenated Bis(hydroxymethyl)-cyclopentenyladenines
Kumamoto H, Imoto S, Amano M, Kuwata-Higashi N, Baba M, Mitsuya H, et al.
ACS Med Chem Lett . 2019 Jan; 9(12):1211-1216. PMID: 30613328
Synthesis of 3'-halogeno analogues (-) of 9-[-4,-5-bis(hydroxymethyl)-cyclopent-2-en--1-yl]-9-adenine (BCA, ) was accomplished by means of dual utilization of the vinyl sulfone functional moieties in both and utilizing a S2' conjugate-addition reaction...