Katrin Richter
Overview
Explore the profile of Katrin Richter including associated specialties, affiliations and a list of published articles.
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42
Citations
873
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Recent Articles
1.
Tuffs C, Dupovac M, Richter K, Holten S, Schaschinger T, Marg O, et al.
Am J Pathol
. 2024 Nov;
195(3):480-493.
PMID: 39566823
Liver fibrosis is characterized by excessive deposition of extracellular matrix due to chronic inflammation of the liver. Hepatic stellate cells (HSCs) become activated and produce increased amounts of extracellular matrix....
2.
Andleeb H, Papke R, Stokes C, Richter K, Herz S, Chiang K, et al.
J Med Chem
. 2024 May;
67(11):8642-8666.
PMID: 38748608
There is an urgent need for nonopioid treatments for chronic and neuropathic pain to provide effective alternatives amid the escalating opioid crisis. This study introduces novel compounds targeting the α9...
3.
Dallanoce C, Richter K, Stokes C, Papotto C, Andleeb H, Thakur G, et al.
ACS Chem Neurosci
. 2024 Feb;
15(4):827-843.
PMID: 38335726
Several lines of evidence have indicated that nicotinic acetylcholine receptors (nAChR) that contain α9 subunits, probably in combination with α10 subunits, may be valuable targets for the management of pain...
4.
Schmidt G, Rienas G, Muller S, Richter K, Sander M, Koch C, et al.
Sci Rep
. 2023 Sep;
13(1):16216.
PMID: 37758747
Mucociliary clearance is a pivotal physiological mechanism that protects the lung by cleaning the airways from pollution and colonization, thereby preventing infection. Ciliary function is influenced by various signal transduction...
5.
Richter K, Herz S, Stokes C, Damaj M, Grau V, Papke R
Neuropharmacology
. 2023 Sep;
240:109717.
PMID: 37758018
Pain due to inflammation can be reduced by targeting the noncanonical nicotinic receptors (NCNR) in cells of the immune system that regulate the synthesis and release of pro- and anti-inflammatory...
6.
Perniss A, Boonen B, Tonack S, Thiel M, Poharkar K, Alnouri M, et al.
Sci Adv
. 2023 Aug;
9(31):eadg8842.
PMID: 37531421
Host-derived succinate accumulates in the airways during bacterial infection. Here, we show that luminal succinate activates murine tracheal brush (tuft) cells through a signaling cascade involving the succinate receptor 1...
7.
Richter K, Asci N, Singh V, Hawro Yakoob S, Meixner M, Zakrzewicz A, et al.
Front Immunol
. 2023 Mar;
14:1140592.
PMID: 36969210
Objective: The pro-inflammatory cytokine interleukin-1β (IL-1β) plays a central role in host defense against infections. High systemic IL-1β levels, however, promote the pathogenesis of inflammatory disorders. Therefore, mechanisms controlling IL-1β...
8.
Richter K, Grau V
Pharmacol Res
. 2023 Mar;
191:106727.
PMID: 36966897
Nicotinic acetylcholine receptors are not only expressed by the nervous system and at the neuro-muscular junction but also by mononuclear phagocytes, which belong to the innate immune system. Mononuclear phagocyte...
9.
Richter K, Amati A, Padberg W, Grau V
Front Pharmacol
. 2022 Sep;
13:981276.
PMID: 36105198
The expression of the acute-phase reactants C-reactive protein (CRP), α1-antitrypsin (AAT), and secretory leukocyte protease inhibitor (SLPI), is induced in response to inflammation by pro-inflammatory mediators, including interleukin-1β. It is...
10.
Ballout J, Classen R, Richter K, Grau V, Diener M
Br J Pharmacol
. 2022 Jul;
179(21):4992-5011.
PMID: 35853139
Background And Purpose: ATP plays an important role as an extracellular messenger acting via different types of purinoceptors. Whereas most of the actions of ATP at intestinal epithelia are thought...