Katrin Richter
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Explore the profile of Katrin Richter including associated specialties, affiliations and a list of published articles.
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42
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873
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Recent Articles
11.
Richter K, Papke R, Stokes C, Roy D, Espinosa E, Wolf P, et al.
Front Cell Neurosci
. 2022 Apr;
16:779081.
PMID: 35431807
Activation of nicotinic acetylcholine receptors (nAChRs) expressed by innate immune cells can attenuate pro-inflammatory responses. Silent nAChR agonists, which down-modulate inflammation but have little or no ionotropic activity, are of...
12.
Richter K, Ogiemwonyi-Schaefer R, Wilker S, Chaveiro A, Agne A, Hecker M, et al.
J Clin Med
. 2020 Sep;
9(9).
PMID: 32906646
Amyloid-β peptide (Aβ), the cleavage product of the evolutionary highly conserved amyloid precursor protein, presumably plays a pathogenic role in Alzheimer's disease. Aβ can induce the secretion of the pro-inflammatory...
13.
Zakrzewicz A, Richter K, Zakrzewicz D, Siebers K, Damm J, Agne A, et al.
Front Immunol
. 2019 Apr;
10:664.
PMID: 31019507
Interleukin-1β (IL-1β) is a potent, pro-inflammatory cytokine of the innate immune system that plays an essential role in host defense against infection. However, elevated circulating levels of IL-1β can cause...
14.
Grau V, Richter K, Hone A, McIntosh J
Front Pharmacol
. 2019 Jan;
9:1499.
PMID: 30687084
Venomous marine snails of the genus employ small peptides to capture prey, mainly osteichthyes, mollusks, and worms. A subset of these peptides known as α-conotoxins, are antagonists of nicotinic acetylcholine...
15.
Richter K, Sagawe S, Hecker A, Kullmar M, Askevold I, Damm J, et al.
Front Immunol
. 2018 Aug;
9:1604.
PMID: 30105015
Blood levels of the acute phase reactant C-reactive protein (CRP) are frequently measured as a clinical marker for inflammation, but the biological functions of CRP are still controversial. CRP is...
16.
Richter K, Koch C, Perniss A, Wolf P, Schweda E, Wichmann S, et al.
Molecules
. 2018 Aug;
23(8).
PMID: 30096783
Phosphocholine-modified bacterial cell wall components are virulence factors enabling immune evasion and permanent colonization of the mammalian host, by mechanisms that are poorly understood. Recently, we demonstrated that free phosphocholine...
17.
Siebers K, Fink B, Zakrzewicz A, Agne A, Richter K, Konzok S, et al.
Front Immunol
. 2018 Jun;
9:877.
PMID: 29922281
While interleukin (IL)-1β is a potent pro-inflammatory cytokine involved in host defense, high levels can cause life-threatening sterile inflammation including systemic inflammatory response syndrome. Hence, the control of IL-1β secretion...
18.
Hiller S, Heldmann S, Richter K, Jurastow I, Kullmar M, Hecker A, et al.
Int J Mol Sci
. 2018 Apr;
19(4).
PMID: 29642561
While interleukin-1β (IL-1β) is a potent pro-inflammatory cytokine essential for host defense, high systemic levels cause life-threatening inflammatory syndromes. ATP, a stimulus of IL-1β maturation, is released from damaged cells...
19.
Marchetti C, Swartzwelter B, Gamboni F, Neff C, Richter K, Azam T, et al.
Proc Natl Acad Sci U S A
. 2018 Jan;
115(7):E1530-E1539.
PMID: 29378952
Activation of the NLRP3 inflammasome induces maturation of IL-1β and IL-18, both validated targets for treating acute and chronic inflammatory diseases. Here, we demonstrate that OLT1177, an orally active β-sulfonyl...
20.
Richter K, Muller-Ladner U, Dischereit G, Uwe L
Curr Rheumatol Rev
. 2017 Aug;
14(2):117-122.
PMID: 28799492
Background: In view of the already existing and the expected growing costs due to the pathological osteoarthritic joint alterations and the related consequences, preventive and conservative strategies which can avoid...