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Kathryn T Bieging

Explore the profile of Kathryn T Bieging including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bieging K, Attardi L
Nature . 2015 Mar; 520(7545):37-8. PMID: 25799989
No abstract available.
2.
Jiang D, LaGory E, Broz D, Bieging K, Brady C, Link N, et al.
Cell Rep . 2015 Feb; 10(7):1096-109. PMID: 25704813
The p53 tumor suppressor plays a key role in maintaining cellular integrity. In response to diverse stress signals, p53 can trigger apoptosis to eliminate damaged cells or cell-cycle arrest to...
3.
Bieging K, Mello S, Attardi L
Nat Rev Cancer . 2014 Apr; 14(5):359-70. PMID: 24739573
p53 is a crucial tumour suppressor that responds to diverse stress signals by orchestrating specific cellular responses, including transient cell cycle arrest, cellular senescence and apoptosis, which are all processes...
4.
Broz D, Mello S, Bieging K, Jiang D, Dusek R, Brady C, et al.
Genes Dev . 2013 May; 27(9):1016-31. PMID: 23651856
The mechanisms by which the p53 tumor suppressor acts remain incompletely understood. To gain new insights into p53 biology, we used high-throughput sequencing to analyze global p53 transcriptional networks in...
5.
Schmidt D, Bieging K, Gomez-de-Leon P, Villasenor-Sierra A, Inostroza J, Robbins J, et al.
Pediatr Infect Dis J . 2012 May; 31(8):876-8. PMID: 22549435
We measured anti-Haemophilus influenzae type a capsular polysaccharide serum immunoglobulin G antibodies in cord blood sera from Mexican (n = 68) and Chilean mothers (n = 72) by enzyme-linked immunosorbent...
6.
Bieging K, Attardi L
Trends Cell Biol . 2011 Dec; 22(2):97-106. PMID: 22154076
p53 is a pivotal tumor suppressor that induces apoptosis, cell-cycle arrest and senescence in response to stress signals. Although p53 transcriptional activation is important for these responses, the mechanisms underlying...
7.
Bieging K, Fish K, Bondada S, Longnecker R
Blood . 2011 Nov; 118(26):6849-59. PMID: 22039254
The link between EBV infection and Burkitt lymphoma (BL) is strong, but the mechanism underlying that link has been elusive. We have developed a mouse model for EBV-associated BL in...
8.
Bieging K, Swanson-Mungerson M, Amick A, Longnecker R
Cell Cycle . 2010 Feb; 9(5):901-8. PMID: 20160479
Burkitt's lymphoma (BL) is characterized by translocation of the MYC gene to an immunoglobulin locus. Transgenic mouse models have been used to study the molecular changes that are necessary to...
9.
Bieging K, Amick A, Longnecker R
Proc Natl Acad Sci U S A . 2009 Oct; 106(42):17945-50. PMID: 19815507
Although Epstein-Barr virus (EBV) is linked to Burkitt's lymphoma (BL), the role of the virus in lymphomagenesis is unclear. LMP2A, encoded by EBV, can be detected in BL biopsies and...
10.
Rabin S, Veesenmeyer J, Bieging K, Hauser A
Infect Immun . 2006 Apr; 74(5):2552-61. PMID: 16622190
ExoU, a phospholipase injected into host cells by the type III secretion system of Pseudomonas aeruginosa, leads to rapid cytolytic cell death. Although the importance of ExoU in infection is...