Katherine E Squires
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Explore the profile of Katherine E Squires including associated specialties, affiliations and a list of published articles.
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12
Citations
238
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Recent Articles
1.
Alexander S, Kelly E, Mathie A, Peters J, Veale E, Armstrong J, et al.
Br J Pharmacol
. 2023 Dec;
180 Suppl 2:S1-S22.
PMID: 38123153
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
2.
Squires K, Ogilvie L, Jucov A, Anastasiy I, Ghicavii N, Huguet J, et al.
J Viral Hepat
. 2022 Oct;
30(1):19-28.
PMID: 36201354
ATI-2173 is an active site polymerase inhibitor nucleotide in development as part of a potentially curative regimen for chronic hepatitis B virus (HBV) infection. This study evaluated the safety, tolerability,...
3.
Friedman P, Sneddon W, Mamonova T, Montanez-Miranda C, Ramineni S, Harbin N, et al.
J Biol Chem
. 2022 Mar;
298(5):101836.
PMID: 35307350
Phosphate homeostasis, mediated by dietary intake, renal absorption, and bone deposition, is incompletely understood because of the uncharacterized roles of numerous implicated protein factors. Here, we identified a novel role...
4.
Alexander S, Kelly E, Mathie A, Peters J, Veale E, Armstrong J, et al.
Br J Pharmacol
. 2021 Sep;
178 Suppl 1:S1-S26.
PMID: 34529830
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
5.
Squires K, Gerber K, Tillman M, Lustberg D, Montanez-Miranda C, Zhao M, et al.
J Biol Chem
. 2021 Jan;
296:100024.
PMID: 33410399
The human genome contains vast genetic diversity as naturally occurring coding variants, yet the impact of these variants on protein function and physiology is poorly understood. RGS14 is a multifunctional...
6.
Squires K, Mayers D, Bluemling G, Kolykhalov A, Guthrie D, Reddy P, et al.
Antimicrob Agents Chemother
. 2020 Jun;
64(9).
PMID: 32540975
ATI-2173 is a novel liver-targeted molecule designed to deliver the 5'-monophosphate of clevudine for the treatment of chronic hepatitis B infection. Unlike other nucleos(t)ides, the active clevudine-5'-triphosphate is a noncompetitive,...
7.
Gerber K, Squires K, Hepler J
J Biol Chem
. 2019 Aug;
294(32):12262.
PMID: 31399537
No abstract available.
8.
Gerber K, Squires K, Hepler J
J Biol Chem
. 2018 Aug;
293(38):14616-14631.
PMID: 30093406
Regulator of G protein signaling 14 (RGS14) is a multifunctional brain scaffolding protein that integrates G protein and Ras/ERK signaling pathways. It is also a nucleocytoplasmic shuttling protein. RGS14 binds...
9.
Squires K, Montanez-Miranda C, Pandya R, Torres M, Hepler J
Pharmacol Rev
. 2018 Jun;
70(3):446-474.
PMID: 29871944
Regulators of G protein signaling (RGS) proteins modulate the physiologic actions of many neurotransmitters, hormones, and other signaling molecules. Human RGS proteins comprise a family of 20 canonical proteins that...
10.
Squires K, Gerber K, Pare J, Branch M, Smith Y, Hepler J
Brain Struct Funct
. 2017 Aug;
223(1):233-253.
PMID: 28776200
Regulator of G protein signaling 14 (RGS14) is a multifunctional signaling protein primarily expressed in mouse pyramidal neurons of hippocampal area CA2 where it regulates synaptic plasticity important for learning...