Katharina Schlereth
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Explore the profile of Katharina Schlereth including associated specialties, affiliations and a list of published articles.
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11
Citations
531
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Recent Articles
1.
Gehrs S, Jakab M, Gutjahr E, Gu Z, Weichenhan D, Mallm J, et al.
Dev Cell
. 2025 Jan;
PMID: 39814015
The labyrinthian fetoplacental capillary network is vital for proper nourishment of the developing embryo. Dysfunction of the maternal-fetal circulation is a primary cause of placental insufficiency. Here, we show that...
2.
Laban H, Siegmund S, Schlereth K, Trogisch F, Ablieh A, Brandenburg L, et al.
Cardiovasc Res
. 2024 Aug;
120(13):1590-1606.
PMID: 39107245
Aims: Chronic hypoxia causes detrimental structural alterations in the lung, which may cause pulmonary hypertension and are partially mediated by the endothelium. While its relevance for the development of hypoxia-associated...
3.
Cheng S, Mittnenzweig M, Mayshar Y, Lifshitz A, Dunjic M, Rais Y, et al.
Cell
. 2022 Jul;
185(17):3169-3185.e20.
PMID: 35908548
Mice deficient for all ten-eleven translocation (TET) genes exhibit early gastrulation lethality. However, separating cause and effect in such embryonic failure is challenging. To isolate cell-autonomous effects of TET loss,...
4.
Pemp D, Esch H, Hauptstein R, Moller F, Zierau O, Bosland M, et al.
Arch Toxicol
. 2019 May;
93(7):1979-1992.
PMID: 31119341
Despite being widely used to investigate 17β-estradiol (E2)-induced mammary gland (MG) carcinogenesis and prevention thereof, estrogen homeostasis and its significance in the female August Copenhagen Irish (ACI) rat model is...
5.
Schlereth K, Weichenhan D, Bauer T, Heumann T, Giannakouri E, Lipka D, et al.
Elife
. 2018 May;
7.
PMID: 29749927
Maintenance of a quiescent and organotypically-differentiated layer of blood vessel-lining endothelial cells (EC) is vital for human health. Yet, the molecular mechanisms of vascular quiescence remain largely elusive. Here we...
6.
Teichert M, Milde L, Holm A, Stanicek L, Gengenbacher N, Savant S, et al.
Nat Commun
. 2017 Jul;
8:16106.
PMID: 28719590
The Tie receptors with their Angiopoietin ligands act as regulators of angiogenesis and vessel maturation. Tie2 exerts its functions through its supposed endothelial-specific expression. Yet, Tie2 is also expressed at...
7.
Schlereth K, Heyl C, Krampitz A, Mernberger M, Finkernagel F, Scharfe M, et al.
PLoS Genet
. 2013 Aug;
9(8):e1003726.
PMID: 23966881
p53 protects us from cancer by transcriptionally regulating tumor suppressive programs designed to either prevent the development or clonal expansion of malignant cells. How p53 selects target genes in the...
8.
Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein R, Biton M, et al.
Cancer Cell
. 2013 Jul;
24(2):242-56.
PMID: 23890787
Senescence, perceived as a cancer barrier, is paradoxically associated with inflammation, which promotes tumorigenesis. Here, we characterize a distinct low-grade inflammatory process in stressed epithelium that is related to para-inflammation;...
9.
Timofeev O, Schlereth K, Wanzel M, Braun A, Nieswandt B, Pagenstecher A, et al.
Cell Rep
. 2013 May;
3(5):1512-25.
PMID: 23665223
Four molecules of the tumor suppressor p53 assemble to cooperatively bind proapoptotic target genes. The structural basis for cooperativity consists of interactions between adjacent DNA binding domains. Mutations at the...
10.
Schlereth K, Charles J, Bretz A, Stiewe T
Cell Cycle
. 2010 Oct;
9(20):4068-76.
PMID: 20948308
The tumor suppressor p53 provides exquisite protection from cancer by balancing cell survival and death in response to stress. Sustained stress or irreparable damage trigger p53's killer functions to permanently...