Kate Haddley
Overview
Explore the profile of Kate Haddley including associated specialties, affiliations and a list of published articles.
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13
Citations
167
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Recent Articles
1.
Powell T, Powell-Smith G, Haddley K, McGuffin P, Quinn J, Schalkwyk L, et al.
Int J Methods Psychiatr Res
. 2014 Mar;
23(2):279-88.
PMID: 24677680
Recent studies have revealed that antidepressants affect the expression of constitutively expressed "housekeeping genes" commonly used as normalizing reference genes in quantitative polymerase chain reaction (qPCR) experiments. There has yet...
2.
DSouza U, Powell-Smith G, Haddley K, Powell T, Bubb V, Price T, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2013 Jun;
162B(5):474-83.
PMID: 23765727
Lamotrigine, a mood stabilizer used clinically in the treatment of bipolar disorder, is thought to exert actions on the serotonin system. However lamotrigine's exact mechanism of action remains unclear. The...
3.
Paredes U, Bubb V, Haddley K, Macho G, Quinn J
J Mol Neurosci
. 2011 Nov;
47(2):401-7.
PMID: 22038691
The serotonin transporter gene (SLC6A4) is heavily involved in the regulation of social behaviour of primates. Old World monkeys (e.g. macaques, baboons) have been used to study interactions between variation...
4.
Aboonq M, Vasiliou S, Haddley K, Quinn J, Bubb V
J Mol Neurosci
. 2011 Jun;
46(1):33-9.
PMID: 21647709
We investigated whether activity-dependent neuroprotective protein (ADNP) could autoregulate its own expression. Both the endogenous ADNP gene and reporter gene constructs were analysed in response to overexpression of ADNP, supplied...
5.
Paredes U, Bubb V, Haddley K, Macho G, Quinn J
BMC Neurosci
. 2011 May;
12:46.
PMID: 21599953
Background: Detecting functional variants contributing to diversity of behaviour is crucial for dissecting genetics of complex behaviours. At a molecular level, characterisation of variation in exons has been studied as...
6.
Vasiliou S, Ali F, Haddley K, Cardoso M, Bubb V, Quinn J
Addict Biol
. 2011 Feb;
17(1):156-70.
PMID: 21309950
We demonstrated that the genotype of the variable number tandem repeats (VNTRs) in the linked polymorphic region (LPR) of the 5' promoter and in the intron 2 (Stin2) transcriptional regulatory...
7.
Haddley K, Spencer E, Vasiliou S, Howard M, Thippeswamy T, Bubb V, et al.
J Mol Neurosci
. 2010 Aug;
45(2):94-100.
PMID: 20690045
In rat hippocampal cultures, the preprotachykinin A (PPTA/Tac1) gene, which encodes the neuropeptide substance P, is regulated by the action of lithium. We used reporter gene and expression constructs to...
8.
Gillies S, Haddley K, Vasiliou S, Jacobson G, von Mentzer B, Bubb V, et al.
J Mol Neurosci
. 2010 Jul;
44(2):77-90.
PMID: 20652837
Neuron-restrictive silencer factor (NRSF) and its isoforms are differentially regulated in rodent models of self-sustaining status epilepticus (SSSE). NRSF isoforms regulate genes associated with SSSE, including the proconvulsant tachykinins, brain-derived...
9.
Ali F, Haddley K, Quinn J
Methods Mol Biol
. 2010 Mar;
628:195-214.
PMID: 20238083
Two alleles of a gene that contain polymorphic cis-regulatory regions can contribute differently to expression levels. Evolutionary changes in such cis-regulatory domains are believed to have participated in the cognitive...
10.
Ali F, Vasiliou S, Haddley K, Paredes U, Roberts J, Miyajima F, et al.
J Neurochem
. 2009 Oct;
112(1):296-306.
PMID: 19860858
Two distinct variable number tandem repeats (VNTRs) within the human serotonin transporter gene (SLC6A4) have been implicated as predisposing factors for CNS disorders. The linked polymorphic region in the 5'-promoter...