Karthikeyan Kandavelou
Overview
Explore the profile of Karthikeyan Kandavelou including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
642
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ramalingam S, Annaluru N, Kandavelou K, Chandrasegaran S
Curr Gene Ther
. 2014 Sep;
14(6):461-72.
PMID: 25245091
Generation and precise genetic correction of patient-derived hiPSCs have great potential in regenerative medicine. Such targeted genetic manipulations can now be achieved using gene-editing nucleases. Here, we report generation of...
2.
Annaluru N, Muller H, Mitchell L, Ramalingam S, Stracquadanio G, Richardson S, et al.
Science
. 2014 Mar;
344(6179):55-8.
PMID: 24674868
Rapid advances in DNA synthesis techniques have made it possible to engineer viruses, biochemical pathways and assemble bacterial genomes. Here, we report the synthesis of a functional 272,871-base pair designer...
3.
Ramalingam S, London V, Kandavelou K, Cebotaru L, Guggino W, Civin C, et al.
Stem Cells Dev
. 2012 Aug;
22(4):595-610.
PMID: 22931452
Zinc finger nucleases (ZFNs) have become powerful tools to deliver a targeted double-strand break at a pre-determined chromosomal locus in order to insert an exogenous transgene by homology-directed repair. ZFN-mediated...
4.
Lim L, Kandavelou K, Khan N
J Am Geriatr Soc
. 2012 May;
60(6):1141-4.
PMID: 22642506
This is a comparison review of GeriaSims and Care of the Aging Medical Patient (CHAMP) modules addressing issues in palliative and hospice medicine found in the Portal of Geriatric Online...
5.
Annaluru N, Muller H, Ramalingam S, Kandavelou K, London V, Richardson S, et al.
Methods Mol Biol
. 2012 Feb;
852:77-95.
PMID: 22328427
Recent advances in DNA synthesis technology make it possible to design and synthesize DNA fragments of several kb in size. However, the process of assembling the smaller DNA fragments into...
6.
Ramalingam S, Kandavelou K, Rajenderan R, Chandrasegaran S
J Mol Biol
. 2010 Nov;
405(3):630-41.
PMID: 21094162
Zinc-finger nucleases (ZFNs) have emerged as powerful tools for delivering a targeted genomic double-strand break (DSB) to either stimulate local homologous recombination with investigator-provided donor DNA or induce gene mutations...
7.
Kandavelou K, Ramalingam S, London V, Mani M, Wu J, Alexeev V, et al.
Biochem Biophys Res Commun
. 2009 Jul;
388(1):56-61.
PMID: 19635463
Targeted introduction of a double-stranded break (DSB) using designer zinc finger nucleases (ZFNs) in mammalian cells greatly enhances gene targeting - homologous recombination (HR) at a chosen endogenous target gene,...
8.
Custom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes
Kandavelou K, Chandrasegaran S
Methods Mol Biol
. 2009 Jun;
544:617-36.
PMID: 19488728
Zinc finger nucleases (ZFNs) are custom-designed molecular scissors, engineered to cut at specific DNA sequences. ZFNs combine the zinc finger proteins (ZFPs) with the nonspecific cleavage domain of the FokI...
9.
Lamichhane G, Raghunand T, Morrison N, Woolwine S, Tyagi S, Kandavelou K, et al.
J Infect Dis
. 2006 Oct;
194(9):1233-40.
PMID: 17041849
The in vivo rate of proliferation of Mycobacterium tuberculosis, the causative agent of tuberculosis, has been linked to the rate of progression and severity of disease. Here, we report that...
10.
Durai S, Mani M, Kandavelou K, Wu J, Porteus M, Chandrasegaran S
Nucleic Acids Res
. 2005 Oct;
33(18):5978-90.
PMID: 16251401
Custom-designed zinc finger nucleases (ZFNs), proteins designed to cut at specific DNA sequences, are becoming powerful tools in gene targeting--the process of replacing a gene within a genome by homologous...