Sivaprakash Ramalingam
Overview
Explore the profile of Sivaprakash Ramalingam including associated specialties, affiliations and a list of published articles.
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41
Citations
517
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Recent Articles
1.
Ala C, Ramalingam S, Kondapalli Venkata Gowri C, Sankaranarayanan M
Life Sci
. 2025 Mar;
369:123536.
PMID: 40057227
Sickle cell disease (SCD) is one of the most prevalent hereditary blood disorders characterized by aberrant hemoglobin synthesis that causes red blood cells (RBCs) to sickle and result in vaso-occlusion....
2.
Verma S, Dalabehera S, Maurya R, Singh D, Prasher B, Pandey R, et al.
Stem Cell Res
. 2024 Aug;
81:103539.
PMID: 39179505
No abstract available.
3.
Ala C, Joshi R, Gupta P, Goswami S, Ramalingam S, Kondapalli Venkata Gowri C, et al.
Arch Pharm (Weinheim)
. 2024 Jul;
357(11):e2400381.
PMID: 39031925
Sickle cell disease (SCD) is an autosomal recessive genetic disorder that occurs due to the point mutation in the β-globin gene, which results in the formation of sickle hemoglobin (HbS)...
4.
Sahel D, Goswami S, Jatyan R, Tharmatt A, Singh V, Dalela M, et al.
Int J Biol Macromol
. 2024 May;
271(Pt 2):132426.
PMID: 38820904
Eye-related diseases, specifically retinal dystrophy (RD) conditions, are the leading cause of blindness worldwide. Gene addition, regulation, or editing could potentially treat such diseases through gene expression regulation. CRISPR/Cas9 gene...
5.
Verma S, Dalabehera S, Maurya R, Singh D, Prasher B, Pandey R, et al.
Stem Cell Res
. 2024 May;
78:103456.
PMID: 38820863
Rubinstein Taybi Syndrome (RSTS) is a rare genetic disorder which is caused by mutations in either CREBBP or EP300. RSTS with mutations in CREBBP is known as RSTS-1. We have...
6.
Marothia M, Behl A, Maurya P, Saini M, Shoaib R, Garg S, et al.
iScience
. 2024 May;
27(6):109918.
PMID: 38812541
Malaria parasite invasion to host erythrocytes is mediated by multiple interactions between merozoite ligands and erythrocyte receptors that contribute toward the development of disease pathology. Here, we report a novel...
7.
Sarangi P, Kumar N, Sambasivan R, Ramalingam S, Amit S, Chandra D, et al.
Thromb Res
. 2024 May;
238:151-160.
PMID: 38718473
It is crucial to develop a long-term therapy that targets hemophilia A and B, including inhibitor-positive patients. We have developed an Adeno-associated virus (AAV) based strategy to integrate the bypass...
8.
Gupta P, Goswami S, Kumari G, Saravanakumar V, Bhargava N, Rai A, et al.
Nat Commun
. 2024 Feb;
15(1):1794.
PMID: 38413594
Ex vivo cellular system that accurately replicates sickle cell disease and β-thalassemia characteristics is a highly sought-after goal in the field of erythroid biology. In this study, we present the...
9.
Gupta P, Arvinden V, Thakur P, Bhoyar R, Saravanakumar V, Gottumukkala N, et al.
Front Mol Biosci
. 2023 Dec;
10:1244244.
PMID: 38152111
β-hemoglobinopathies such as β-thalassemia (BT) and Sickle cell disease (SCD) are inherited monogenic blood disorders with significant global burden. Hence, early and affordable diagnosis can alleviate morbidity and reduce mortality...
10.
McCulloch L, Sambasivam V, Hughes A, Annaluru N, Ramalingam S, Fanfani V, et al.
Cell Genom
. 2023 Nov;
3(11):100419.
PMID: 38020974
We describe the complete synthesis, assembly, debugging, and characterization of a synthetic 404,963 bp chromosome, (synthetic chromosome ). Combined chromosome construction methods were used to synthesize and integrate its left...