Karine Dubrana
Overview
Explore the profile of Karine Dubrana including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
24
Citations
763
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Phipps J, Toulouze M, Ducrot C, Costa R, Brocas C, Dubrana K
Nat Cell Biol
. 2024 Nov;
27(1):118-129.
PMID: 39482358
DNA double-strand breaks (DSBs) must be repaired to ensure genome stability. Crucially, DSB-ends must be kept together for timely repair. In Saccharomyces cerevisiae, two pathways mediate DSB end-tethering. One employs...
2.
Simon M, Dubrana K, Palancade B
Curr Opin Genet Dev
. 2024 Jan;
84:102150.
PMID: 38215626
Nuclear organization has emerged as a critical layer in the coordination of DNA repair activities. Distinct types of DNA lesions have notably been shown to relocate at the vicinity of...
3.
Penzo A, Dubarry M, Brocas C, Zheng M, Mangione R, Rougemaille M, et al.
Nat Commun
. 2023 Sep;
14(1):5606.
PMID: 37730746
Nuclear pore complexes (NPCs) have increasingly recognized interactions with the genome, as exemplified in yeast, where they bind transcribed or damaged chromatin. By combining genome-wide approaches with live imaging of...
4.
Maloisel L, Ma E, Phipps J, Deshayes A, Mattarocci S, Marcand S, et al.
PLoS Genet
. 2023 Feb;
19(2):e1010639.
PMID: 36749784
The bypass of DNA lesions that block replicative polymerases during DNA replication relies on DNA damage tolerance pathways. The error-prone translesion synthesis (TLS) pathway depends on specialized DNA polymerases that...
5.
Phipps J, Dubrana K
Genes (Basel)
. 2022 Feb;
13(2).
PMID: 35205243
DNA double-strand breaks (DSBs) are a deleterious form of DNA damage, which must be robustly addressed to ensure genome stability. Defective repair can result in chromosome loss, point mutations, loss...
6.
Bordelet H, Costa R, Brocas C, Depagne J, Veaute X, Busso D, et al.
EMBO J
. 2021 Nov;
41(1):e108813.
PMID: 34817085
Heterochromatin is a conserved feature of eukaryotic chromosomes, with central roles in gene expression regulation and maintenance of genome stability. How heterochromatin proteins regulate DNA repair remains poorly described. In...
7.
Forey R, Barthe A, Tittel-Elmer M, Wery M, Barrault M, Ducrot C, et al.
Mol Cell
. 2020 Dec;
81(1):183-197.e6.
PMID: 33278361
Mre11-Rad50-Xrs2 (MRX) is a highly conserved complex with key roles in various aspects of DNA repair. Here, we report a new function for MRX in limiting transcription in budding yeast....
8.
Mojumdar A, Sorenson K, Hohl M, Toulouze M, Lees-Miller S, Dubrana K, et al.
Cell Rep
. 2019 Aug;
28(6):1564-1573.e3.
PMID: 31390569
Non-homologous end joining (NHEJ) and homologous recombination (HR) are the two major pathways of DNA double-strand break (DSB) repair and both are highly conserved from yeast to mammals. Nej1 has...
9.
Condensin-Mediated Chromosome Folding and Internal Telomeres Drive Dicentric Severing by Cytokinesis
Guerin T, Beneut C, Barinova N, Lopez V, Lazar-Stefanita L, Deshayes A, et al.
Mol Cell
. 2019 Jun;
75(1):131-144.e3.
PMID: 31204167
In Saccharomyces cerevisiae, dicentric chromosomes stemming from telomere fusions preferentially break at the fusion. This process restores a normal karyotype and protects chromosomes from the detrimental consequences of accidental fusions....
10.
Brocas C, Ducrot C, Dubrana K
Methods Mol Biol
. 2019 Jun;
2004:17-24.
PMID: 31147906
The cohesin complex is required to establish sister chromatid cohesion and ensure accurate chromosome segregation after DNA replication. Recent data has also revealed a role for cohesion as a major...