Karen T Barker
Overview
Explore the profile of Karen T Barker including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
264
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0
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Recent Articles
1.
Barker K, Yogev O
Methods Mol Biol
. 2022 Jul;
2535:73-83.
PMID: 35867223
The vast majority of cancer deaths are the result of drug resistance. The lack of superior preclinical models that better reflect the complexity of relapsed disease hinders the development of...
2.
Yogev O, Almeida G, Barker K, George S, Kwok C, Campbell J, et al.
Cancer Res
. 2019 Aug;
79(20):5382-5393.
PMID: 31405846
Neuroblastoma is a pediatric cancer that is frequently metastatic and resistant to conventional treatment. In part, a lack of natively metastatic, chemoresistant models has limited our insight into the development...
3.
Abbaszadeh F, Barker K, McConville C, Scott R, Rahman N
Fam Cancer
. 2010 Jan;
9(3):425-30.
PMID: 20054657
Wilms tumor and neuroblastoma are childhood tumors of the kidney and undifferentiated neural crest cells, respectively. Both disorders are primarily sporadic, but familial Wilms tumor pedigrees and familial neuroblastoma pedigrees...
4.
Barker K, Spendlove H, Banu N, Bridge J, Fisher C, Shipley J, et al.
Cancer Lett
. 2005 Jun;
235(1):136-40.
PMID: 15949892
Germline mutations in Fumarate Hydratase (FH) cause the development of leiomyomas and leiomyosarcomas in the syndromes Multiple Cutaneous and Uterine Leiomyomata (MCUL1) and Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC)....
5.
Spendlove H, Damato B, Humphreys J, Barker K, Hiscott P, Houlston R
Melanoma Res
. 2004 Dec;
14(6):449-52.
PMID: 15577314
Activating mutations in exon 15 of BRAF have been detected in a high proportion of cutaneous melanomas. To determine whether such mutations are a feature of conjunctival or uveal melanomas,...
6.
Sellick G, Barker K, Stolte-Dijkstra I, Fleischmann C, Coleman R, Garrett C, et al.
Nat Genet
. 2004 Nov;
36(12):1301-5.
PMID: 15543146
Individuals with permanent neonatal diabetes mellitus usually present within the first three months of life and require insulin treatment. We recently identified a locus on chromosome 10p13-p12.1 involved in permanent...
7.
Barker K, Houlston R
Eur J Hum Genet
. 2003 Aug;
11(9):665-70.
PMID: 12939652
Studies in drosophila and animal models have shown that the phosphoinositide-3-kinase (PI3-kinase) axis plays a central role in normal development, defining the number and size of cells in tissues. Dysfunction...