Kami Ahmad
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Explore the profile of Kami Ahmad including associated specialties, affiliations and a list of published articles.
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61
Citations
4654
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Recent Articles
11.
Henikoff S, Henikoff J, Ahmad K, Paranal R, Janssens D, Russell Z, et al.
Nat Commun
. 2023 Sep;
14(1):5930.
PMID: 37739938
For more than a century, formalin-fixed paraffin-embedded (FFPE) sample preparation has been the preferred method for long-term preservation of biological material. However, the use of FFPE samples for epigenomic studies...
12.
Wooten M, Takushi B, Ahmad K, Henikoff S
Sci Adv
. 2023 Jun;
9(24):eadg3257.
PMID: 37315134
Anthracyclines are a class of widely prescribed anticancer drugs that disrupt chromatin by intercalating into DNA and enhancing nucleosome turnover. To understand the molecular consequences of anthracycline-mediated chromatin disruption, we...
13.
Wooten M, Takushi B, Ahmad K, Henikoff S
bioRxiv
. 2023 Jan;
PMID: 36712130
Anthracyclines are a class of widely prescribed anti-cancer drugs that disrupt chromatin by intercalating into DNA and enhancing nucleosome turnover. To understand the molecular consequences of anthracycline-mediated chromatin disruption, we...
14.
Ahmad K, Henikoff S
Fac Rev
. 2023 Jan;
11:40.
PMID: 36644296
The control of gene expression in eukaryotes relies on how transcription factors and RNA polymerases manipulate the structure of chromatin. These interactions are especially important in development as gene expression...
15.
De Sarkar N, Patton R, Doebley A, Hanratty B, Adil M, Kreitzman A, et al.
Cancer Discov
. 2022 Nov;
13(3):632-653.
PMID: 36399432
Significance: This study provides insights into the dynamics of nucleosome positioning and gene regulation associated with cancer phenotypes that can be ascertained from ctDNA. New methods for classification in phenotype...
16.
Khyzha N, Henikoff S, Ahmad K
Nat Methods
. 2022 Oct;
19(11):1383-1392.
PMID: 36192462
Whereas techniques to map chromatin-bound proteins are well developed, mapping chromatin-associated RNAs remains a challenge. Here, we describe Reverse Transcribe and Tagment (RT&Tag), in which RNAs associated with a chromatin...
17.
Henikoff S, Ahmad K
Protein Sci
. 2022 Sep;
31(11):e4458.
PMID: 36170035
Technological progress over the past 15 years has fueled an explosion in genome-wide chromatin profiling tools that take advantage of low-cost short-read sequencing technologies to map particular chromatin features. Here,...
18.
Chen T, Wei X, Courret C, Cui M, Cheng L, Wu J, et al.
PLoS Genet
. 2022 Sep;
18(9):e1010351.
PMID: 36048878
Advances in genomic technology led to a more focused pattern for the distribution of chromosomal proteins and a better understanding of their functions. The recent development of the CUT&RUN technique...
19.
20.
Ahmad K, Henikoff S, Ramachandran S
Annu Rev Biochem
. 2022 Mar;
91:183-195.
PMID: 35303789
Gene regulation arises out of dynamic competition between nucleosomes, transcription factors, and other chromatin proteins for the opportunity to bind genomic DNA. The timescales of nucleosome assembly and binding of...