Kaley M Wilburn
Overview
Explore the profile of Kaley M Wilburn including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
245
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Recent Articles
1.
Fieweger R, Wilburn K, Montague C, Roszkowski E, Kelly C, Southard T, et al.
J Biol Chem
. 2023 Jan;
299(3):102910.
PMID: 36642182
Lipids are important nutrients for Mycobacterium tuberculosis (Mtb) to support bacterial survival in mammalian tissues and host cells. Fatty acids and cholesterol are imported across the Mtb cell wall via...
2.
Wilburn K, Meade R, Heckenberg E, Dockterman J, Coers J, Sassetti C, et al.
Infect Immun
. 2023 Jan;
91(2):e0051022.
PMID: 36629440
Mycobacterium tuberculosis () is a bacterium that exclusively resides in human hosts and remains a dominant cause of morbidity and mortality among infectious diseases worldwide. Host protection against infection is...
3.
Brown K, Wilburn K, Montague C, Grigg J, Sanz O, Perez-Herran E, et al.
Antimicrob Agents Chemother
. 2023 Jan;
67(1):e0129422.
PMID: 36602336
Despite the deployment of combination tuberculosis (TB) chemotherapy, efforts to identify shorter, nonrelapsing treatments have resulted in limited success. Recent evidence indicates that GSK2556286 (GSK286), which acts via Rv1625c, a...
4.
Theriault M, Pisu D, Wilburn K, Le-Bury G, MacNamara C, Petrassi H, et al.
Commun Biol
. 2022 Jul;
5(1):685.
PMID: 35810253
Mycobacterium tuberculosis (Mtb), the cause of the human pulmonary disease tuberculosis (TB), contributes to approximately 1.5 million deaths every year. Prior work has established that lipids are actively catabolized by...
5.
Wilburn K, Montague C, Qin B, Woods A, Love M, McNamara C, et al.
PLoS Pathog
. 2022 Feb;
18(2):e1009862.
PMID: 35134095
There is a growing appreciation for the idea that bacterial utilization of host-derived lipids, including cholesterol, supports Mycobacterium tuberculosis (Mtb) pathogenesis. This has generated interest in identifying novel antibiotics that...
6.
Fieweger R, Wilburn K, VanderVen B
Microorganisms
. 2019 Jun;
7(6).
PMID: 31216777
Pathogenic mycobacteria are known for their ability to maintain persistent infections in various mammals. The canonical pathogen in this genus is and this bacterium is particularly successful at surviving and...
7.
Wilburn K, Fieweger R, VanderVen B
Pathog Dis
. 2018 May;
76(2).
PMID: 29718271
Tuberculosis is a distinctive disease in which the causative agent, Mycobacterium tuberculosis, can persist in humans for decades by avoiding clearance from host immunity. During infection, M. tuberculosis maintains viability...
8.
Nazarova E, Montague C, La T, Wilburn K, Sukumar N, Lee W, et al.
Elife
. 2017 Jul;
6.
PMID: 28708968
Pathogenic bacteria have evolved highly specialized systems to extract essential nutrients from their hosts. (Mtb) scavenges lipids (cholesterol and fatty acids) to maintain infections in mammals but mechanisms and proteins...
9.
Wilburn K, Mwandumba H, Jambo K, Boliar S, Solouki S, Russell D, et al.
Retrovirology
. 2016 Aug;
13(1):55.
PMID: 27515378
8E5/LAV cells harbor a single HIV provirus, and are used frequently to generate standards for HIV genome quantification. Using flow cytometry-based in situ mRNA hybridization validated by qPCR, we find...