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K Tangemann

Explore the profile of K Tangemann including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 629
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Recent Articles
1.
Tangemann K, Bistrup A, Hemmerich S, Rosen S
J Exp Med . 1999 Oct; 190(7):935-42. PMID: 10510083
During lymphocyte homing, L-selectin mediates the tethering and rolling of lymphocytes on high endothelial venules (HEVs) in secondary lymphoid organs. The L-selectin ligands on HEV are a set of mucin-like...
2.
Strausbaugh H, Green P, Lo E, Tangemann K, Reichling D, Rosen S, et al.
Nat Med . 1999 Sep; 5(9):1057-61. PMID: 10470085
Although the inflammatory response is essential for protecting tissues from injury and infection, unrestrained inflammation can cause chronic inflammatory diseases such as arthritis, colitis and asthma. Physiological mechanisms that downregulate...
3.
Prakobphol A, Tangemann K, Rosen S, Hoover C, Leffler H, Fisher S
Biochemistry . 1999 May; 38(21):6817-25. PMID: 10346903
The low-molecular-weight human salivary mucin (MG2) coats oral surfaces, where it is in a prime location for governing cell adhesion. Since oligosaccharides form many of the interactive facets on mucin...
4.
Tangemann K, Gunn M, Giblin P, Rosen S
J Immunol . 1998 Dec; 161(11):6330-7. PMID: 9834123
The homing of lymphocytes to secondary lymphoid organs is thought to involve the action of chemokines. Secondary lymphoid-tissue chemokine (SLC), a high endothelial venule (HEV)-associated chemokine, has emerged as a...
5.
Sassetti C, Tangemann K, Singer M, Kershaw D, Rosen S
J Exp Med . 1998 Jun; 187(12):1965-75. PMID: 9625756
The leukocyte adhesion molecule, L-selectin, mediates the recruitment of lymphocytes to secondary lymphoid organs via interactions with specific ligands presented on high endothelial venules (HEV). Although the HEV-derived ligands for...
6.
Gunn M, Tangemann K, Tam C, Cyster J, Rosen S, Williams L
Proc Natl Acad Sci U S A . 1998 Feb; 95(1):258-63. PMID: 9419363
Preferential homing of naive lymphocytes to secondary lymphoid organs is thought to involve the action of chemokines, yet no chemokine has been shown to have either the expression pattern or...
7.
Erb E, Tangemann K, Bohrmann B, Muller B, Engel J
Biochemistry . 1997 Jun; 36(24):7395-402. PMID: 9200686
Integrin activation, ligand binding, and integrin clustering were analyzed using alphaIIb beta3 reconstituted into phospholipid vesicles and into supported planar lipid bilayers. Strong and specific binding of fibrinogen and the...
8.
Rivas G, Tangemann K, Minton A, Engel J
J Mol Recognit . 1996 Jan; 9(1):31-8. PMID: 8723317
Fibrinogen showed essentially no binding (KD > 1 mM) to platelet alpha IIb beta 3 integrin in solution in the presence of Triton or octylglucoside above critical micellar concentrations. Under...
9.
Pfaff M, Sasaki T, Tangemann K, Chu M, Timpl R
Exp Cell Res . 1995 Jul; 219(1):87-92. PMID: 7543056
The extracellular matrix proteins fibulin-1 (variants C and D) and fibulin-2 occur in basement membranes and in vessel walls and are thus potential candidates for cellular interactions. Recombinant forms of...
10.
Tangemann K, Engel J
FEBS Lett . 1995 Jan; 358(2):179-81. PMID: 7530218
To clarify the question as to why different solid-phase assays yield different results in terms of interaction strength, we used fibrinogen binding to immobilized alpha IIb beta 3 integrin as...