D B Reichling
Overview
Explore the profile of D B Reichling including associated specialties, affiliations and a list of published articles.
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25
Citations
1001
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Recent Articles
1.
Parada C, Reichling D, Levine J
Pain
. 2004 Dec;
113(1-2):185-90.
PMID: 15621379
Toward the goal of defining new pharmacological targets for the treatment of chronic pain conditions, in previous studies we established a model, termed 'hyperalgesic priming,' in which an acute inflammatory...
2.
Parada C, Yeh J, Reichling D, Levine J
Neuroscience
. 2003 Jul;
120(1):219-26.
PMID: 12849754
Recently we demonstrated that a single 3-day episode of carrageenan-induced acute cutaneous inflammation can create a chronic state of increased susceptibility to inflammatory hyperalgesia. In this latent "primed" state, although...
3.
Khasar S, Reichling D, Green P, Isenberg W, Levine J
Neuroscience
. 2003 May;
119(1):215-21.
PMID: 12763082
The vagus nerve modulates nociception by a mechanism dependent upon gonadal hormones and the adrenal medulla. In the present study we tested the hypothesis that this modulation is dynamically controlled...
4.
Tanner K, Reichling D, Gear R, Paul S, Levine J
Neuroscience
. 2003 Apr;
118(3):809-17.
PMID: 12710988
It is known that the level of activity in nociceptive primary afferent nerve fibers increases in neuropathic conditions that produce pain, but changes in the temporal patterning of action potentials...
5.
6.
McCarter G, Reichling D, Levine J
Neurosci Lett
. 1999 Oct;
273(3):179-82.
PMID: 10515188
Although it is generally presumed that mechanical sensitivity of somatosensory nerve fibers results from the activation of mechanosensitive ion channels, a mechanically-gated whole-cell current has never been demonstrated in dorsal...
7.
Strausbaugh H, Green P, Lo E, Tangemann K, Reichling D, Rosen S, et al.
Nat Med
. 1999 Sep;
5(9):1057-61.
PMID: 10470085
Although the inflammatory response is essential for protecting tissues from injury and infection, unrestrained inflammation can cause chronic inflammatory diseases such as arthritis, colitis and asthma. Physiological mechanisms that downregulate...
8.
Tanner K, Reichling D, Levine J
J Neurosci
. 1998 Aug;
18(16):6480-91.
PMID: 9698336
Neuropathic pain accompanies peripheral nerve injury after a wide variety of insults including metabolic disorders, traumatic nerve injury, and neurotoxic drugs. Chemotherapy-induced neuropathic pain, caused by drugs such as vincristine...
9.
Gold M, Reichling D, Hampl K, Drasner K, Levine J
J Pharmacol Exp Ther
. 1998 May;
285(2):413-21.
PMID: 9580578
Evidence from both clinical studies and animal models suggests that the local anesthetic, lidocaine, is neurotoxic. However, the mechanism of lidocaine-induced toxicity is unknown. To test the hypothesis that toxicity...
10.
Reichling D, Levine J
Proc Natl Acad Sci U S A
. 1997 Jun;
94(13):7006-11.
PMID: 9192682
The mechanism of heat transduction in vertebrate sensory neurons was investigated in vitro by using cultured dorsal root ganglion neurons from adult rat. In response to a physiologically relevant range...