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K R Gregor

Explore the profile of K R Gregor including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 26
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Recent Articles
1.
Burke J, Davern L, Stanley P, Gregor K, Banville J, Remillard R, et al.
J Pharmacol Exp Ther . 2001 Jun; 298(1):376-85. PMID: 11408565
Cytosolic phospholipase A2 (cPLA2) catalyzes the selective release of arachidonic acid from the sn-2 position of phospholipids and is believed to play a key cellular role in the generation of...
2.
SPRINGER D, Luh B, Bronson J, McElhone K, Mansuri M, Gregor K, et al.
Bioorg Med Chem . 2000 Jul; 8(5):1087-109. PMID: 10882020
Twenty-four hydrophobic dicarboxylic acids are described which were evaluated as inhibitors of 14 kDa human platelet phospholipase A2 (HP-PLA2). In general, biarylacetic acid derivatives were found to be more active...
3.
Burke J, Witmer M, Zusi F, Gregor K, Davern L, Padmanabha R, et al.
J Biol Chem . 1999 Jun; 274(27):18864-71. PMID: 10383382
Cytosolic phospholipase A2 (cPLA2) catalyzes the selective release of arachidonic acid from the sn-2 position of phospholipids and is believed to play a key cellular role in the generation of...
4.
Burke J, Davern L, Gregor K, Owczarczak L
Biochem Biophys Res Commun . 1999 Jun; 260(1):232-9. PMID: 10381372
Treatment with dibutyryl cyclic AMP (dBcAMP) of the human, premonocytic U937 cell line results in differentiation toward a monocyte/granulocyte-like cell. This differentiation enables the cell to activate cytosolic phospholipase A2...
5.
Burke J, Gregor K, Padmanabha R, Banville J, Witmer M, Davern L, et al.
J Enzyme Inhib . 1998 Jun; 13(3):195-206. PMID: 9629537
Cytosolic phospholipase A2 (cPLA2) catalyzes the selective release of arachidonic acid from the sn-2 position of phospholipids and is believed to play a key cellular role in the generation of...
6.
Burke J, Davern L, Gregor K, Tramposch K
Biochim Biophys Acta . 1997 Dec; 1359(1):80-8. PMID: 9398088
Leukotriene B4 (LTB4) is a potent lipid mediator of inflammation and is involved in the receptor-mediated activation of a number of leukocyte responses including degranulation, superoxide formation, and chemotaxis. In...
7.
Burke J, Davern L, Gregor K, Todderud G, Alford J, Tramposch K
Biochim Biophys Acta . 1997 Nov; 1341(2):223-37. PMID: 9357962
Differentiation with dibutyryl cyclic AMP (dBcAMP) of the human, premonocytic U937 cell line toward a monocyte/granulocyte-like cell results in the cell acquiring an ability to release arachidonate upon stimulation. In...
8.
Burke J, Witmer M, Tredup J, Micanovic R, Gregor K, Lahiri J, et al.
Biochemistry . 1995 Nov; 34(46):15165-74. PMID: 7578131
Cytosolic phospholipase A2 (cPLA2) hydrolyzes the sn-2 ester of phospholipids and is believed to be responsible for the receptor-regulated release of arachidonic acid from phospholipid pools. The enzyme was assayed...
9.
Burke J, Gregor K, Tramposch K
J Biol Chem . 1995 Jan; 270(1):274-80. PMID: 7814386
Many important mediators of inflammation result from the liberation of free arachidonic acid from phospholipid pools which is thought to result from the action of phospholipase A2 (PLA2). It is...
10.
Isseroff H, Sylvester P, Bessette C, Jones P, Fisher W, Rynkowski T, et al.
Comp Biochem Physiol A Comp Physiol . 1989 Jan; 94(1):41-5. PMID: 2571452
1. Radioimmunoassay of the opiate, beta-endorphin, in mouse sera, indirect measurement of estrogen by examination of vaginal smears and indirect measurement of androgens by electrophoresis of major urinary proteins (MUP)...