K H Kaestner
Overview
Explore the profile of K H Kaestner including associated specialties, affiliations and a list of published articles.
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Articles
59
Citations
4136
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0
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Recent Articles
1.
Vazquez Salgado A, Preziosi M, Yin D, Holczbauer A, Zahm A, Erez N, et al.
Gastro Hep Adv
. 2022 Sep;
1(5):905-908.
PMID: 36117551
No abstract available.
2.
Kolev H, Tian Y, Kim M, Leu N, Adams-Tzivelekidis S, Lengner C, et al.
Cell Mol Gastroenterol Hepatol
. 2021 May;
12(3):1155-1158.e4.
PMID: 34029742
No abstract available.
3.
Helman A, Avrahami D, Klochendler A, Glaser B, Kaestner K, Ben-Porath I, et al.
Diabetes Obes Metab
. 2016 Sep;
18 Suppl 1:58-62.
PMID: 27615132
Ageing is generally associated with deterioration of organ function and regenerative potential. In the case of pancreatic β-cells, an age-related decline in proliferative potential is well documented, and was proposed...
4.
Turner J, Ray R, Lee B, Everett L, Xiang J, Jepson C, et al.
Mol Psychiatry
. 2013 Sep;
19(7):801-10.
PMID: 23999525
Addiction to nicotine and the ability to quit smoking are influenced by genetic factors. We used functional genomic approaches (chromatin immunoprecipitation (ChIP) and whole-genome sequencing) to identify cAMP response element-binding...
5.
Hald J, Galbo T, Rescan C, Radzikowski L, Sprinkel A, Heimberg H, et al.
Diabetologia
. 2011 Sep;
55(1):154-65.
PMID: 21947380
Aims/hypothesis: The aim of the study was to identify surface bio-markers and corresponding antibody tools that can be used for the imaging and immunoisolation of the pancreatic beta cell and...
6.
Dorrell C, Schug J, Lin C, Canaday P, Fox A, Smirnova O, et al.
Diabetologia
. 2011 Sep;
54(11):2832-44.
PMID: 21882062
Aims/hypothesis: We sought to determine the mRNA transcriptome of all major human pancreatic endocrine and exocrine cell subtypes, including human alpha, beta, duct and acinar cells. In addition, we identified...
7.
Bramswig N, Kaestner K
Diabetes Obes Metab
. 2011 Aug;
13 Suppl 1:13-20.
PMID: 21824252
The development of the endocrine pancreas and the differentiation of its five cell types, α, β, δ, ε and pancreatic polypeptide (PP) cells, are a highly complex and tightly regulated...
8.
Zhao J, Schug J, Li M, Kaestner K, Grant S
Diabetologia
. 2010 Jul;
53(11):2340-6.
PMID: 20640398
Aims/hypothesis: Transcription factor 7-like 2 (TCF7L2) has been strongly implicated in type 2 diabetes and cancer. Our goal was to identify the DNA sequences bound by this transcription factor in...
9.
Ghaleb A, Katz J, Kaestner K, Du J, Yang V
Oncogene
. 2006 Oct;
26(16):2365-73.
PMID: 17016435
In response to gamma-radiation-induced DNA damage, organisms either activate cell cycle checkpoint and repair machinery or undergo apoptosis to eliminate damaged cells. Although previous studies indicated that the tumor suppressor...
10.
Friedman J, Kaestner K
Cell Mol Life Sci
. 2006 Aug;
63(19-20):2317-28.
PMID: 16909212
The Foxa subfamily of winged helix/forkhead box (Fox) transcription factors has been the subject of genetic and biochemical study for over 15 years. During this time its three members, Foxa1,...