K H Grabstein
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Explore the profile of K H Grabstein including associated specialties, affiliations and a list of published articles.
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82
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3627
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Recent Articles
1.
Mossman S, Evans L, Fang H, Staas J, Tice T, Raychaudhuri S, et al.
Vaccine
. 2005 Apr;
23(27):3545-54.
PMID: 15855013
With the ultimate goal of developing a therapeutic cancer vaccine, we encapsulated the Her-2/neu peptide p369-377 in poly(lactide-co-glycolide) microspheres. This formulation was found to effectively elicit CD8+ cytotoxic T cell...
2.
Borges M, Campos-Neto A, Sleath P, Grabstein K, Morrissey P, Skeiky Y, et al.
Infect Immun
. 2001 Aug;
69(9):5270-7.
PMID: 11500395
The interaction of the innate immune system with the microbial world involves primarily two sets of molecules generally known as microbial pattern recognition receptors and microbial pattern recognition molecules, respectively....
3.
Lewinsohn D, Zhu L, Madison V, Dillon D, Fling S, Reed S, et al.
J Immunol
. 2000 Dec;
166(1):439-46.
PMID: 11123322
Previous studies in murine and human models have suggested an important role for HLA Ia-restricted CD8(+) T cells in host defense to Mycobacterium tuberculosis (Mtb). Therefore, understanding the Ags presented...
4.
Lewinsohn D, Briden A, Reed S, Grabstein K, Alderson M
J Immunol
. 2000 Jul;
165(2):925-30.
PMID: 10878367
Previous studies in mice and humans models have suggested an important role for CD8+ T cells in host defense to Mycobacterium tuberculosis (Mtb). In humans, CD8+ Mtb-reactive T cells have...
5.
Disis M, Grabstein K, Sleath P, Cheever M
Clin Cancer Res
. 1999 Jul;
5(6):1289-97.
PMID: 10389911
HER-2/neu is a "self" tumor antigen that is overexpressed in 15-30% of human adenocarcinomas. Vaccine strategies directed against HER-2/neu and other self tumor antigens require development of methods to overcome...
6.
Groh V, Rhinehart R, Secrist H, Bauer S, Grabstein K, Spies T
Proc Natl Acad Sci U S A
. 1999 Jun;
96(12):6879-84.
PMID: 10359807
Human MHC class I-related molecules, MICA and MICB, are stress-induced antigens that are recognized by a subset of gamma delta T cells expressing the variable region Vdelta1. This functional association...
7.
Skeiky Y, Kennedy M, Kaufman D, Borges M, Guderian J, Scholler J, et al.
J Immunol
. 1998 Dec;
161(11):6171-9.
PMID: 9834103
We have evaluated the ability of the Leishmania protein LeIF to influence the Th1/Th2 cytokine responses and the generation of LeIF-specific T cell clones in the absence of adjuvant. We...
8.
Tuttle T, Anderson B, Thompson W, Lee J, Sahin A, Smith T, et al.
Clin Cancer Res
. 1998 Aug;
4(8):2015-24.
PMID: 9717833
Previous studies have characterized the reactivity of CD8+ CTLs with ovarian and breast cancer. There is little information about the antigens and epitopes recognized by CD4+ T cells in these...
9.
Lewinsohn D, Alderson M, Briden A, Riddell S, Reed S, Grabstein K
J Exp Med
. 1998 Jun;
187(10):1633-40.
PMID: 9584141
Previous studies in murine models, including those using the beta2 microglobulin knockout mouse, have suggested an important role for CD8+ T cells in host defense to Mycobacterium tuberculosis (Mtb). At...
10.
Lewinsohn D, Bement T, Xu J, Lynch D, Grabstein K, Reed S, et al.
J Immunol
. 1998 Mar;
160(5):2374-9.
PMID: 9498779
CTL, both CD4+ and CD8+, are essential in the eradication of intracellular pathogens. Data generated using murine T cells have suggested a critical role for CD95 (Fas, Apo-1) in CD4+...