R J Armitage
Overview
Explore the profile of R J Armitage including associated specialties, affiliations and a list of published articles.
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Articles
91
Citations
3072
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Recent Articles
1.
Gordon J, Grafton G, WOOD P, Larche M, Armitage R
Curr Opin Pharmacol
. 2001 Nov;
1(4):431-5.
PMID: 11710744
The mouse is now the animal of choice for laboratory-based medical research. Although its contribution to advancing understanding of our inner workings is indisputable, we should acknowledge that mice and...
2.
Vonderheide R, Dutcher J, Anderson J, Eckhardt S, Stephans K, Razvillas B, et al.
J Clin Oncol
. 2001 Jul;
19(13):3280-7.
PMID: 11432896
Purpose: To determine the toxicity, maximum-tolerated dose (MTD), and pharmacokinetics of recombinant human CD40 ligand (rhuCD40L) (Avrend; Immunex Corp, Seattle, WA), suggested in preclinical studies to mediate cytotoxicity against CD40-expressing...
3.
Gordon J, Challa A, Levens J, Gregory C, Williams J, Armitage R, et al.
Cell Death Differ
. 2000 Oct;
7(9):785-94.
PMID: 11042673
Owing to its lineage and differentiation stage-restricted expression, CD77 has been mooted as a therapeutic target in Burkitt lymphoma (BL). The recognition that the globotriaosyl moiety of this neutral glycosphingolipid...
4.
Armitage R
J Biol Regul Homeost Agents
. 2000 Jun;
14(2):145-7.
PMID: 10841293
No abstract available.
5.
Armitage R
J Biol Regul Homeost Agents
. 2000 Jun;
14(2):142-4.
PMID: 10841292
No abstract available.
6.
Kubin M, Parshley D, Din W, Waugh J, Smith C, Macduff B, et al.
Eur J Immunol
. 1999 Nov;
29(11):3466-77.
PMID: 10556801
Using the monoclonal antibody C1.7, which recognizes a signaling, membrane-bound molecule on human NK and a proportion of CD8(+) T cells, we cloned a novel molecule we refer to as...
7.
Challa A, Pound J, Armitage R, Gordon J
Allergy
. 1999 Aug;
54(6):576-83.
PMID: 10435471
Background: The induction of IgE synthesis in naive B cells requires two T-cell-derived signals: one delivered through CD40 and the other via interleukin-4 (IL-4). The natural counterstructure to CD40 is...
8.
Pound J, Challa A, Holder M, Armitage R, Dower S, Fanslow W, et al.
Int Immunol
. 1999 Mar;
11(1):11-20.
PMID: 10050669
Eight different CD40 mAb shared with soluble trimeric CD40 ligand (sCD40LT) the capacity to rescue germinal center (GC) B cells from spontaneous apoptosis and to suppress antigen receptor-driven apoptosis in...
9.
Morris A, Remmele Jr R, Klinke R, Macduff B, Fanslow W, Armitage R
J Biol Chem
. 1998 Dec;
274(1):418-23.
PMID: 9867859
Recent progress in the understanding of immune function indicates that the interaction of CD40L with its receptor, CD40, plays a pivotal role in both humoral immunity and cell-mediated defense against...
10.
Baker M, Eliopoulos A, Young L, Armitage R, Gregory C, Gordon J
Blood
. 1998 Oct;
92(8):2830-43.
PMID: 9763568
Group I Burkitt lymphoma (BL) cell lines (L3055, Elijah, Louckes, BL2, and BL29) retaining the original biopsy phenotype were found to undergo prolonged phenotypic, functional, and molecular change on short-term...