K Cameron Falkner
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Explore the profile of K Cameron Falkner including associated specialties, affiliations and a list of published articles.
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28
Citations
948
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Recent Articles
1.
Wahlang B, Hardesty J, Jin J, Falkner K, Cave M
Curr Opin Toxicol
. 2021 Sep;
14:21-28.
PMID: 34485777
Polychlorinated biphenyls (PCBs) have been associated with abnormal liver enzymes and suspected nonalcoholic fatty liver disease (NAFLD) in cohort studies. NAFLD affects greater than 25% of the global population and...
2.
Jin J, Wahlang B, Shi H, Hardesty J, Falkner K, Head K, et al.
Med Chem Res
. 2020 Aug;
29:1247-1263.
PMID: 32831531
Polychlorinated biphenyls (PCBs) are persistent organic pollutants associated with metabolic disruption and non-alcoholic fatty liver disease (NAFLD). Based on their ability to activate the aryl hydrocarbon receptor (AhR), PCBs are...
3.
Shi H, Jin J, Hardesty J, Falkner K, Prough R, Balamurugan A, et al.
Toxicol Appl Pharmacol
. 2020 Jul;
404:115149.
PMID: 32702359
No abstract available.
4.
Wahlang B, Appana S, Falkner K, McClain C, Brock G, Cave M
Environ Sci Pollut Res Int
. 2019 Dec;
27(6):6476-6487.
PMID: 31873887
Non-alcoholic fatty liver disease (NAFLD), the most common form of liver disease, affects over 30% of the US population. Our group and others have previously demonstrated that low-level environmental pollutant...
5.
Vatsalya V, Cave M, Kong M, Gobejishvili L, Falkner K, Craycroft J, et al.
Clin Gastroenterol Hepatol
. 2019 Dec;
18(9):2046-2054.
PMID: 31811953
Background & Aims: Acute alcoholic hepatitis (AAH) is a major cause of liver-related morbidity and mortality; there are no good blood biomarkers for diagnosis or determining magnitude of cell death....
6.
Wahlang B, Jin J, Beier J, Hardesty J, Daly E, Schnegelberger R, et al.
Curr Environ Health Rep
. 2019 May;
6(3):80-94.
PMID: 31134516
Purpose: Fatty liver disease (FLD) affects over 25% of the global population and may lead to liver-related mortality due to cirrhosis and liver cancer. FLD caused by occupational and environmental...
7.
Wahlang B, Jin J, Hardesty J, Head K, Shi H, Falkner K, et al.
Food Chem Toxicol
. 2019 Apr;
129:64-76.
PMID: 31026535
Exposures to persistent environmental pollutants like polychlorinated biphenyls (PCBs) has been associated with liver diseases such as toxicant-associated steatohepatitis (TASH). However, previously published PCB hepatotoxicity studies evaluated mostly male animal...
8.
Shi H, Hardesty J, Jin J, Head K, Falkner K, Cave M, et al.
Xenobiotica
. 2019 Apr;
49(12):1414-1422.
PMID: 30991879
1. Aryl hydrocarbon receptor (AhR) ligands, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs), are endocrine disrupting chemicals associated with nonalcoholic fatty liver disease. This study documents the species-specific differences between...
9.
Hardesty J, Wahlang B, Falkner K, Shi H, Jin J, Zhou Y, et al.
J Proteome Res
. 2019 Feb;
18(4):1582-1594.
PMID: 30807179
Environmental pollution contributes to fatty liver disease pathogenesis. Polychlorinated biphenyl (PCB) exposures have been associated with liver enzyme elevation and suspected steatohepatitis in cohort studies. Male mice treated with the...
10.
Shi H, Jan J, Hardesty J, Falkner K, Prough R, Balamurugan A, et al.
Toxicol Appl Pharmacol
. 2018 Oct;
363:22-33.
PMID: 30312631
The endocrine disrupting chemicals, polychlorinated biphenyls (PCBs), have been associated with nonalcoholic steatohepatitis (NASH) and diabetes. However, an integrative analysis of the effects of PCBs on the liver and pancreas...