Justin G Laughlin
Overview
Explore the profile of Justin G Laughlin including associated specialties, affiliations and a list of published articles.
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4
Citations
82
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Recent Articles
1.
Francis E, Laughlin J, Dokken J, Finsberg H, Lee C, Rognes M, et al.
Nat Comput Sci
. 2025 Feb;
5(2):185.
PMID: 39901055
No abstract available.
2.
Francis E, Laughlin J, Dokken J, Finsberg H, Lee C, Rognes M, et al.
Nat Comput Sci
. 2024 Dec;
5(1):76-89.
PMID: 39702839
Biological cells rely on precise spatiotemporal coordination of biochemical reactions to control their functions. Such cell signaling networks have been a common focus for mathematical models, but they remain challenging...
3.
Lee C, Laughlin J, Angliviel de La Beaumelle N, Amaro R, McCammon J, Ramamoorthi R, et al.
PLoS Comput Biol
. 2020 Apr;
16(4):e1007756.
PMID: 32251448
Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to...
4.
An Open-Source Mesh Generation Platform for Biophysical Modeling Using Realistic Cellular Geometries
Lee C, Laughlin J, Moody J, Amaro R, McCammon J, Holst M, et al.
Biophys J
. 2020 Feb;
118(5):1003-1008.
PMID: 32032503
Advances in imaging methods such as electron microscopy, tomography, and other modalities are enabling high-resolution reconstructions of cellular and organelle geometries. Such advances pave the way for using these geometries...
5.
Sriram K, Laughlin J, Rangamani P, Tartakovsky D
Biophys J
. 2016 Jul;
111(1):208-21.
PMID: 27410748
We present a biochemical model of the wall shear stress-induced activation of endothelial nitric oxide synthase (eNOS) in an endothelial cell. The model includes three key mechanotransducers: mechanosensing ion channels,...