Michael Holst
Overview
Explore the profile of Michael Holst including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
106
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0
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Recent Articles
1.
Vasan R, Rowan M, Lee C, Johnson G, Rangamani P, Holst M
Front Phys
. 2022 Oct;
7.
PMID: 36188416
In this perspective, we examine three key aspects of an end-to-end pipeline for realistic cellular simulations: reconstruction and segmentation of cellular structures; generation of cellular structures; and mesh generation, simulation,...
2.
Lee C, Laughlin J, Angliviel de La Beaumelle N, Amaro R, McCammon J, Ramamoorthi R, et al.
PLoS Comput Biol
. 2020 Apr;
16(4):e1007756.
PMID: 32251448
Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to...
3.
An Open-Source Mesh Generation Platform for Biophysical Modeling Using Realistic Cellular Geometries
Lee C, Laughlin J, Moody J, Amaro R, McCammon J, Holst M, et al.
Biophys J
. 2020 Feb;
118(5):1003-1008.
PMID: 32032503
Advances in imaging methods such as electron microscopy, tomography, and other modalities are enabling high-resolution reconstructions of cellular and organelle geometries. Such advances pave the way for using these geometries...
4.
Stolerman L, Getz M, Llewellyn Smith S, Holst M, Rangamani P
Bull Math Biol
. 2020 Feb;
82(2):30.
PMID: 32025918
Protein aggregation on the plasma membrane (PM) is of critical importance to many cellular processes such as cell adhesion, endocytosis, fibrillar conformation, and vesicle transport. Lateral diffusion of protein aggregates...
5.
Grogan F, Holst M, Lindblom L, Amaro R
J Chem Phys
. 2017 Dec;
147(23):234106.
PMID: 29272950
Molecular dynamics (MD) simulations are used in biochemistry, physics, and other fields to study the motions, thermodynamic properties, and the interactions between molecules. Computational limitations and the complexity of these...
6.
Adaptive Finite Element Method for Solving the Exact Kohn-Sham Equation of Density Functional Theory
Bylaska E, Holst M, Weare J
J Chem Theory Comput
. 2015 Nov;
5(4):937-48.
PMID: 26609603
No abstract available.
7.
Balasubramanian M, Arias-Castro E, Medeiros F, Kriegman D, Bowd C, Weinreb R, et al.
Invest Ophthalmol Vis Sci
. 2014 Feb;
55(3):1684-95.
PMID: 24519427
Purpose: We evaluated three new pixelwise rates of retinal height changes (PixR) strategies to reduce false-positive errors while detecting glaucomatous progression. Methods: Diagnostic accuracy of nonparametric PixR-NP cluster test (CT),...
8.
Liao T, Zhang Y, Kekenes-Huskey P, Cheng Y, Michailova A, McCulloch A, et al.
Mol Based Math Biol
. 2013 Dec;
1.
PMID: 24352481
Multi-scale modeling plays an important role in understanding the structure and biological functionalities of large biomolecular complexes. In this paper, we present an efficient computational framework to construct multi-scale models...
9.
Gao Z, Yu Z, Holst M
Graph Models
. 2013 Apr;
75(1):23-38.
PMID: 23580890
A method of triangular surface mesh smoothing is presented to improve angle quality by extending the original optimal Delaunay triangulation (ODT) to surface meshes. The mesh quality is improved by...
10.
Gao Z, Yu Z, Holst M
Comput Aided Geom Des
. 2012 Nov;
29(9):707-721.
PMID: 23144522
Despite its great success in improving the quality of a tetrahedral mesh, the original optimal Delaunay triangulation (ODT) is designed to move only inner vertices and thus cannot handle input...