Emmet A Francis
Overview
Explore the profile of Emmet A Francis including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
41
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Recent Articles
1.
Francis E, Laughlin J, Dokken J, Finsberg H, Lee C, Rognes M, et al.
Nat Comput Sci
. 2025 Feb;
5(2):185.
PMID: 39901055
No abstract available.
2.
Francis E, Laughlin J, Dokken J, Finsberg H, Lee C, Rognes M, et al.
Nat Comput Sci
. 2024 Dec;
5(1):76-89.
PMID: 39702839
Biological cells rely on precise spatiotemporal coordination of biochemical reactions to control their functions. Such cell signaling networks have been a common focus for mathematical models, but they remain challenging...
3.
Francis E, Rangamani P
J Cell Sci
. 2024 Aug;
137(17).
PMID: 39140137
Mechanotransduction, which is the integration of mechanical signals from the external environment of a cell to changes in intracellular signaling, governs many cellular functions. Recent studies have shown that the...
4.
Francis E, Rangamani P
Biophys J
. 2024 Mar;
123(9):1031-1033.
PMID: 38549374
No abstract available.
5.
Boero E, Gorham Jr R, Francis E, Brand J, Teng L, Doorduijn D, et al.
Sci Rep
. 2023 Jan;
13(1):274.
PMID: 36609665
The complement system provides vital immune protection against infectious agents by labeling them with complement fragments that enhance phagocytosis by immune cells. Many details of complement-mediated phagocytosis remain elusive, partly...
6.
Francis E, Xiao H, Teng L, Heinrich V
Biophys J
. 2022 Oct;
121(23):4714-4728.
PMID: 36242516
Complex motions of immune cells are an integral part of diapedesis, chemotaxis, phagocytosis, and other vital processes. To better understand how immune cells execute such motions, we present a detailed...
7.
Francis E, Heinrich V
PLoS Comput Biol
. 2022 Aug;
18(8):e1009937.
PMID: 36026476
The dynamic interplay between cell adhesion and protrusion is a critical determinant of many forms of cell motility. When modeling cell spreading on adhesive surfaces, traditional mathematical treatments often consider...
8.
Francis E, Heinrich V
Yale J Biol Med
. 2018 Sep;
91(3):279-289.
PMID: 30258315
Most current efforts to advance medical technology proceed along one of two tracks. The first is dedicated to the improvement of clinical tasks through the incremental refinement of medical instruments....
9.
Francis E, Heinrich V
Sci Signal
. 2018 Mar;
11(521).
PMID: 29535263
Global bursts in free intracellular calcium (Ca) are among the most conspicuous signaling events in immune cells. To test the common view that Ca bursts mediate rearrangement of the actin...
10.
Heinrich V, Simpson 3rd W, Francis E
Front Immunol
. 2017 Jun;
8:578.
PMID: 28603522
The ability of motile immune cells to detect and follow gradients of chemoattractant is critical to numerous vital functions, including their recruitment to sites of infection and-in emerging immunotherapeutic applications-to...