Justin Elstrott
Overview
Explore the profile of Justin Elstrott including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
1664
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Power D, Elstrott J, Schallek J
bioRxiv
. 2024 Jun;
PMID: 38854151
In response to central nervous system (CNS) injury, tissue resident immune cells such as microglia and circulating systemic neutrophils are often first responders. The degree to which these cells interact...
2.
Etxeberria A, Shen Y, Vito S, Silverman S, Imperio J, Lalehzadeh G, et al.
J Neurosci
. 2024 Jun;
44(29.
PMID: 38830764
Human genetics and preclinical studies have identified key contributions of TREM2 to several neurodegenerative conditions, inspiring efforts to modulate TREM2 therapeutically. Here, we characterize the activities of three TREM2 agonist...
3.
Lu Y, Mu L, Elstrott J, Fu C, Sun C, Su T, et al.
EBioMedicine
. 2024 Mar;
102:105045.
PMID: 38471394
Background: Schizophrenia, a debilitating psychiatric disorder, displays considerable interindividual variation in clinical presentations. The ongoing debate revolves around whether this heterogeneity signifies a continuum of severity linked to a singular...
4.
Terrett J, Ly J, Katavolos P, Hasselgren C, Laing S, Zhong F, et al.
J Med Chem
. 2024 Mar;
67(5):3287-3306.
PMID: 38431835
Transient receptor potential ankyrin 1 (TRPA1) is a nonselective calcium ion channel highly expressed in the primary sensory neurons, functioning as a polymodal sensor for exogenous and endogenous stimuli, and...
5.
Byrnes A, Roudnicky F, Gogineni A, Soung A, Xiong M, Hayne M, et al.
Cell Rep Methods
. 2024 Jan;
4(1):100673.
PMID: 38171361
While antisense oligonucleotides (ASOs) are used in the clinic, therapeutic development is hindered by the inability to assay ASO delivery and activity in vivo. Accordingly, we developed a dual-fluorescence, knockin...
6.
Jones M, Orozco L, Qin H, Truong T, Caplazi P, Elstrott J, et al.
Front Cell Dev Biol
. 2023 Sep;
11:1252547.
PMID: 37691820
Rare coding variants cause retinal dystrophy with early macular involvement via unknown mechanisms. We found that is ubiquitously expressed in the human eye and expression changes were observed in eyes...
7.
Castiglioni A, Yang Y, Williams K, Gogineni A, Lane R, Wang A, et al.
Nat Commun
. 2023 Aug;
14(1):4703.
PMID: 37543621
TGFβ signaling is associated with non-response to immune checkpoint blockade in patients with advanced cancers, particularly in the immune-excluded phenotype. While previous work demonstrates that converting tumors from excluded to...
8.
Krishnamurty A, Shyer J, Thai M, Gandham V, Buechler M, Yang Y, et al.
Nature
. 2022 Sep;
611(7934):148-154.
PMID: 36171287
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (LRRC15). However, the...
9.
Hu D, Yun J, Elstrott J, Jasper H
Nat Commun
. 2021 Dec;
12(1):7150.
PMID: 34887411
Tissue regeneration after injury requires coordinated regulation of stem cell activation, division, and daughter cell differentiation, processes that are increasingly well understood in many regenerating tissues. How accurate stem cell...
10.
Dai B, Hackney J, Ichikawa R, Nguyen A, Elstrott J, Orozco L, et al.
Cell Rep Med
. 2021 Sep;
2(8):100381.
PMID: 34467254
Anti-integrins are therapeutically effective for inflammatory bowel disease, yet the relative contribution of α4β7 and αEβ7 to gut lymphocyte trafficking is not fully elucidated. Here, we evaluate the effect of...