Jun-Zhe Wang
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Explore the profile of Jun-Zhe Wang including associated specialties, affiliations and a list of published articles.
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10
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25
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Recent Articles
1.
Li Y, Zhang M, Shimadate Y, Kato A, Wang J, Jia Y, et al.
Org Biomol Chem
. 2025 Feb;
PMID: 39976182
C-2 Fluorinated castanospermines have been synthesized from a well-protected aldehyde precursor and evaluated as glycosidase inhibitors in comparison with castanospermine, 1--castanospermine and C-1 fluorinated castanospermines. While C-1 fluorinated castanospermines lose...
2.
Zi D, Shimadate Y, Wang J, Kato A, Li Y, Jia Y, et al.
Org Biomol Chem
. 2023 Mar;
21(13):2729-2741.
PMID: 36916165
A series of DAB-peptide and DAB-dipeptide derivatives were synthesized from D-tartrate-derived nitrone 18. The DAB peptides 16 are derivatives of ,-3,4-dihydroxy-L-proline. Glycosidase inhibition assay found four of them to be...
3.
Zi D, Song Y, Lu T, Kise M, Kato A, Wang J, et al.
Eur J Med Chem
. 2023 Jan;
247:115056.
PMID: 36603505
A series of α-1-C-alkyl DAB (1,4-dideoxy-1,4-imino-d-arabinitol) and LAB (1,4-dideoxy-1,4-imino-l-arabinitol) derivatives with aryl substituents have been designed as analogues of broussonetine W (12), and assayed as glycosidase inhibitors. While the inhibition...
4.
Li Y, Wang J, Shimadate Y, Kise M, Kato A, Jia Y, et al.
Eur J Med Chem
. 2022 Nov;
244:114852.
PMID: 36332547
A series of C-6 fluorinated casuarine derivatives have been synthesized via organocatalytic stereoselective α-fluorination of iminosugar-based aldehydes or direct nucleophilic fluorination of polyhydroxylated pyrrolizidines. Glycosidase assays against various glycosidases allowed...
5.
Wang J, Shimadate Y, Kise M, Kato A, Jia Y, Li Y, et al.
Eur J Med Chem
. 2022 Jun;
238:114499.
PMID: 35675756
Enantiomeric series of C-4 hydroxymethyl depleted DAB and LAB derivatives (trans, trans-2-C-aryl-3,4-dihydroxypyrrolidines), designed as β-glucosidase inhibitors by molecular docking calculations, have been synthesized in 2 steps from l- and d-tartaric...
6.
Li Y, Wang J, Shimadate Y, Kise M, Kato A, Jia Y, et al.
J Org Chem
. 2022 May;
87(11):7291-7307.
PMID: 35584209
C-7-fluorinated derivatives of two important polyhydroxylated pyrrolizidines, casuarine and australine, were synthesized with organocatalytic stereoselective α-fluorination of aldehydes as the key step. The strategy is extensively applicable to some synthetically...
7.
Wang J, Cheng B, Kato A, Kise M, Shimadate Y, Jia Y, et al.
Eur J Med Chem
. 2022 Mar;
233:114230.
PMID: 35255314
Two series of C-4 alkylated and arylated LAB (1,4-dideoxy-1,4-imino-l-arabinitol) and DAB (1,4-dideoxy-1,4-imino-d-arabinitol) derivatives, synthesized in 6 steps from enantiomeric cyclic nitrones derived from l- and d-tartaric acid, were designed and...
8.
Li Y, Wang J, Kato A, Shimadate Y, Kise M, Jia Y, et al.
Org Biomol Chem
. 2021 Oct;
19(43):9410-9420.
PMID: 34668913
Four diastereomers belonging to the family of casuarines, including casuarine (1), 6--casuarine (2), 7--casuarine (13) and 6,7-di-casuarine (14), have been synthesized from D-arabinose-derived cyclic nitrone 7 and nitrone-derived aldehyde 4...
9.
Lu J, Lai H, Shih W, Chen Y, Huang S, Chang H, et al.
J Supercomput
. 2021 Aug;
78(3):3843-3882.
PMID: 34421218
is an effective statistical arbitrage strategy considering the spread of paired stocks in a stable cointegration relationship. Nevertheless, rapid market changes may break the relationship (namely structural break), which further...
10.
Lu T, Shimadate Y, Cheng B, Kanekiyo U, Kato A, Wang J, et al.
Eur J Med Chem
. 2021 Aug;
224:113716.
PMID: 34340042
5-C-Alkyl-DNJ and 5-C-alkyl-l-ido-DNJ derivatives have been designed and synthesized efficiently from an l-sorbose-derived cyclic nitrone. The DNJ and l-ido-DNJ derivatives with C-5 alkyl chains ranging from methyl to dodecyl were...