Jun-Dong Li
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Explore the profile of Jun-Dong Li including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
433
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Recent Articles
1.
Yang D, Duan M, Yuan Q, Li Z, Luo C, Cui L, et al.
J Transl Med
. 2023 Sep;
21(1):586.
PMID: 37658364
Background: As the most lethal gynecologic cancer, ovarian cancer (OV) holds the potential of being immunotherapy-responsive. However, only modest therapeutic effects have been achieved by immunotherapies such as immune checkpoint...
2.
Yang D, Huang F, Wei W, Li Q, Wu J, Huang Y, et al.
Int J Biol Sci
. 2023 Apr;
19(6):1846-1860.
PMID: 37063431
In recent years, homologous recombination deficiency (HRD) has not achieved the expected substantial promotion of immunotherapeutic efficacy in ovarian cancer. This study aims to explore the role of HRD functional...
3.
Huang H, Nie C, Liu X, Song B, Yue J, Xu J, et al.
J Clin Invest
. 2022 Jun;
132(15).
PMID: 35727633
BACKGROUNDAdoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) has achieved remarkable clinical efficacy in metastatic cancers such as melanoma and cervical cancer (CC). Here, we explored the safety, feasibility, and...
4.
Yu Y, Peng X, Qian X, Zhang K, Huang X, Chen Y, et al.
Signal Transduct Target Ther
. 2021 Dec;
6(1):401.
PMID: 34848680
Met tyrosine kinase, a receptor for a hepatocyte growth factor (HGF), plays a critical role in tumor growth, metastasis, and drug resistance. Mitochondria are highly dynamic and undergo fission and...
5.
Liu M, Ma J, Li J, Sun J, Zhou H, Guan S, et al.
J Pain Res
. 2021 Nov;
14:3411-3419.
PMID: 34754234
Objective: The present study aims to explore the effectiveness and safety of low-dose strong opioids compared with non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of mild cancer pain. Methods: From...
6.
Li X, Yang K, Chen W, Mai J, Wu X, Sun T, et al.
Autophagy
. 2021 May;
17(12):4323-4340.
PMID: 33977871
Macroautophagy/autophagy plays an important role during the development of human cancer. BECN1 (beclin 1), a core player in autophagy regulation, is downregulated in many kinds of malignancy. The underlying mechanism,...
7.
Huang H, Feng Y, Wan T, Zhang Y, Cao X, Huang Y, et al.
JAMA Oncol
. 2021 Jan;
7(3):361-369.
PMID: 33443541
Importance: There is no current consensus on the role of chemotherapy in addition to radiation for postoperative adjuvant treatment of patients with early-stage cervical cancer with adverse pathological factors. Objective:...
8.
Li J, Qiu Z, Liu Z, Zhou Q, Feng L, Li J, et al.
Obes Facts
. 2020 Dec;
14(1):108-120.
PMID: 33352568
Objectives: The impact of heterogeneity on gender difference for achieving clinically meaningful weight loss (cmWL) remains unclear. Here, we explored the potential gender differences in factors associated with cmWL. Methods:...
9.
Deng R, Zhang H, Huang J, Cai R, Wang Y, Chen Y, et al.
Autophagy
. 2020 Nov;
17(10):3011-3029.
PMID: 33213267
The function of mitophagy in cancer is controversial. ULK1 is critical for induction of macroautophagy/autophagy and has a more specific role in mitophagy in response to hypoxia. Here, we show...
10.
Lan C, Wang Y, Xiong Y, Li J, Shen J, Li Y, et al.
Lancet Oncol
. 2018 Aug;
19(9):1239-1246.
PMID: 30082170
Background: Anti-angiogenic therapy combined with chemotherapy could improve the outcomes of patients with platinum-resistant ovarian cancer. Apatinib is an oral tyrosine kinase inhibitor that selectively inhibits VEGF receptor 2. We...