Julien Marquevielle
Overview
Explore the profile of Julien Marquevielle including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
122
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Recent Articles
1.
Malard F, Wolter A, Marquevielle J, Morvan E, Ecoutin A, Rudisser S, et al.
Nucleic Acids Res
. 2024 Mar;
52(8):4124-4136.
PMID: 38554107
Pharmacological modulation of RNA splicing by small molecules is an emerging facet of drug discovery. In this context, the SMN2 splicing modifier SMN-C5 was used as a prototype to understand...
2.
De Rache A, Marquevielle J, Bouaziz S, Vialet B, Andreola M, Mergny J, et al.
J Mol Biol
. 2023 Nov;
436(2):168359.
PMID: 37952768
Nucleic acid sequences containing guanine tracts are able to form non-canonical DNA or RNA structures known as G-quadruplexes (or G4s). These structures, based on the stacking of G-tetrads, are involved...
3.
Luo Y, Granzhan A, Marquevielle J, Cucchiarini A, Lacroix L, Amrane S, et al.
Biochimie
. 2023 Jan;
214(Pt A):5-23.
PMID: 36596406
Besides the well-known DNA double-helix, non-canonical nucleic acid structures regulate crucial biological activities. Among these oddities, guanine-rich DNA sequences can form unusual four-stranded secondary structures called G-quadruplexes (G4s). G4-prone sequences...
4.
Kabbara A, Vialet B, Marquevielle J, Bonnafous P, Mackereth C, Amrane S
Front Chem
. 2022 Dec;
10:1014663.
PMID: 36479439
COVID-19 (Corona Virus Disease 2019), SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) are infectious diseases each caused by coronavirus outbreaks. Small molecules and other therapeutics are...
5.
Robert C, Marquevielle J, Salgado G
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361696
MST1R (RON) is a receptor of the MET tyrosine kinase receptor family involved in several cancers such as pancreas, breast, ovary, colon, and stomach. Some studies have shown that overexpression...
6.
Marquevielle J, De Rache A, Vialet B, Morvan E, Mergny J, Amrane S
Nucleic Acids Res
. 2022 Jun;
50(12):7134-7146.
PMID: 35736226
The Caenorhabditis elegans model has greatly contributed to the understanding of the role of G-quadruplexes in genomic instability. The GGCTTA repeats of the C. elegans telomeres resemble the GGGTTA repeats...
7.
Ferino A, Marquevielle J, Choudhary H, Cinque G, Robert C, Bourdoncle A, et al.
ACS Omega
. 2021 Dec;
6(49):34092-34106.
PMID: 34926957
Recent studies have proven that the genetic landscape of pancreatic cancer is dominated by the oncogene. Its transcription is controlled by a G-rich motif (called 32R) located immediately upstream of...
8.
Marquevielle J, Robert C, Lagrabette O, Wahid M, Bourdoncle A, Xodo L, et al.
Nucleic Acids Res
. 2020 May;
48(16):9336-9345.
PMID: 32432667
KRAS is one of the most mutated oncogenes and still considered an undruggable target. An alternative strategy would consist in targeting its gene rather than the protein, specifically the formation...
9.
Marquevielle J, Vasantha Kumar M, Mergny J, Salgado G
Biomol NMR Assign
. 2017 Dec;
12(1):123-127.
PMID: 29189986
Single stranded guanine rich DNA (or RNA) sequences adopt noncanonical secondary structures called G-quadruplexes (G4). Functionally, quadruplexes control gene transcription and regulate activities such as replication, gene recombination or alternative...
10.
Carvalho J, Pereira E, Marquevielle J, Campello M, Mergny J, Paulo A, et al.
Biochimie
. 2017 Nov;
144:144-152.
PMID: 29129745
KRAS is often found mutated in lethal cancers and should be an important target for anticancer drug development. However, no effective inhibitor has been reported so far, prompting the scientific...