Gilmar F Salgado
Overview
Explore the profile of Gilmar F Salgado including associated specialties, affiliations and a list of published articles.
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33
Citations
490
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Recent Articles
1.
Santos T, Silva M, Imbert L, Campello M, Paulo A, Amrane S, et al.
Chemistry
. 2023 Apr;
29(39):e202301181.
PMID: 37115041
The structural determinants of the interaction of the G-quadruplex (G4) motif found in precursor miRNA 149 (rG4) with the acridine orange derivative C , a G4 ligand stabilizer possessing anticancer...
2.
Robert C, Marquevielle J, Salgado G
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361696
MST1R (RON) is a receptor of the MET tyrosine kinase receptor family involved in several cancers such as pancreas, breast, ovary, colon, and stomach. Some studies have shown that overexpression...
3.
Santos T, Miranda A, Imbert L, Monchaud D, Salgado G, Cabrita E, et al.
J Pharm Biomed Anal
. 2022 Apr;
215:114757.
PMID: 35462282
Let-7e precursor microRNA has the potential to adopt a G-quadruplex (rG4) structure and recently, its roles in oncology have been the focus of much attention, as it is now known...
4.
Santos T, Salgado G, Cabrita E, Cruz C
Trends Cell Biol
. 2022 Apr;
32(7):561-564.
PMID: 35410819
Nucleolin protein is involved in a plethora of cellular pathways across the nucleolus, nucleus, and cytoplasm. The association of its RNA-binding domain (RBD) and its RGG (arginine-glycine-glycine-rich) domain allows it...
5.
Ferino A, Marquevielle J, Choudhary H, Cinque G, Robert C, Bourdoncle A, et al.
ACS Omega
. 2021 Dec;
6(49):34092-34106.
PMID: 34926957
Recent studies have proven that the genetic landscape of pancreatic cancer is dominated by the oncogene. Its transcription is controlled by a G-rich motif (called 32R) located immediately upstream of...
6.
Santos T, Salgado G, Cabrita E, Cruz C
Pharmaceuticals (Basel)
. 2021 Aug;
14(8).
PMID: 34451866
Progress in the design of G-quadruplex (G4) binding ligands relies on the availability of approaches that assess the binding mode and nature of the interactions between G4 forming sequences and...
7.
Chen J, Cheng M, Salgado G, Stadlbauer P, Zhang X, Amrane S, et al.
Nucleic Acids Res
. 2021 Aug;
49(16):9548-9559.
PMID: 34379785
Genomic sequences susceptible to form G-quadruplexes (G4s) are always flanked by other nucleotides, but G4 formation in vitro is generally studied with short synthetic DNA or RNA oligonucleotides, for which...
8.
Carvalho J, Lopes-Nunes J, Vialet B, Rosado T, Gallardo E, Vale J, et al.
Nanomedicine
. 2021 Jun;
36:102429.
PMID: 34174419
Nanoparticles offer targeted delivery of drugs with minimal toxicity to surrounding healthy tissue and have great potential in the management of human papillomavirus (HPV)-related diseases. We synthesized lipid-modified AS1411 aptamers...
9.
Carvalho J, Lopes-Nunes J, Campello M, Paulo A, Milici J, Meyers C, et al.
Nucleic Acid Ther
. 2020 Oct;
31(1):68-81.
PMID: 33121376
Herein, we report, for the first time, the screening of several ligands in terms of their ability to bind and stabilize G-quadruplexes (G4) found in seven human Papillomavirus (HPV) genomes....
10.
Carvalho J, Mergny J, Salgado G, Queiroz J, Cruz C
Trends Mol Med
. 2020 May;
26(9):848-861.
PMID: 32467069
The clinical applicability of G-quadruplexes (G4s) as anticancer drugs is currently being evaluated. Several G4 ligands and aptamers are undergoing clinical trials following the notable examples of quarfloxin and AS1411,...