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Julianne Martell

Explore the profile of Julianne Martell including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 161
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Recent Articles
1.
Martell J, Seo Y, Bak D, Kingsley S, Tissenbaum H, Weerapana E
Cell Chem Biol . 2016 Aug; 23(8):955-66. PMID: 27499530
In the nematode Caenorhabditis elegans, inactivating mutations in the insulin/IGF-1 receptor, DAF-2, result in a 2-fold increase in lifespan mediated by DAF-16, a FOXO-family transcription factor. Downstream protein activities that...
2.
Hatzios S, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, et al.
Nat Chem Biol . 2016 May; 12(6):466. PMID: 27191648
No abstract available.
3.
Hatzios S, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, et al.
Nat Chem Biol . 2016 Feb; 12(4):268-274. PMID: 26900865
Activity-based protein profiling (ABPP) is a chemoproteomic tool for detecting active enzymes in complex biological systems. We used ABPP to identify secreted bacterial and host serine hydrolases that are active...
4.
Lewallen D, Bicker K, Subramanian V, Clancy K, Slade D, Martell J, et al.
ACS Chem Biol . 2015 Sep; 10(11):2520-8. PMID: 26360112
Anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis (RA) and are routinely used for disease diagnosis. Protein citrullination is also increased in cancer and other autoimmune disorders, suggesting...
5.
Martell J, Weerapana E
Molecules . 2014 Jan; 19(2):1378-93. PMID: 24473203
Activity-based protein profiling (ABPP) is a chemical proteomic technique that enables the interrogation of protein activity directly within complex proteomes. Given the dominant role of posttranslational modifications in regulating protein...
6.
Qian Y, Martell J, Pace N, Ballard T, Johnson D, Weerapana E
Chembiochem . 2013 Jul; 14(12):1410-4. PMID: 23861326
Putting a number on it: Cleavable linkers are widely utilized in proteomics applications. In particular, the azobenzene-based linker cleaves under mild conditions that are mass-spectrometry-compatible. Here, we adapt this linker...