Julian Bertschinger
Overview
Explore the profile of Julian Bertschinger including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
143
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Recent Articles
1.
Klupsch K, Baeriswyl V, Scholz R, Dannenberg J, Santimaria R, Senn D, et al.
Leukemia
. 2018 Sep;
33(3):805-808.
PMID: 30206306
No abstract available.
2.
Silacci M, Lembke W, Woods R, Attinger-Toller I, Baenziger-Tobler N, Batey S, et al.
MAbs
. 2015 Sep;
8(1):141-9.
PMID: 26390837
Biologic treatment options such as tumor necrosis factor (TNF) inhibitors have revolutionized the treatment of inflammatory diseases, including rheumatoid arthritis. Recent data suggest, however, that full and long-lasting responses to...
3.
Brack S, Attinger-Toller I, Schade B, Mourlane F, Klupsch K, Woods R, et al.
Mol Cancer Ther
. 2014 Jul;
13(8):2030-9.
PMID: 24994770
Upregulation of HER2 is a hallmark of 20% to 30% of invasive breast cancers, rendering this receptor an attractive target for cancer therapy. Although HER2-targeting agents have provided substantial clinical...
4.
Silacci M, Baenziger-Tobler N, Lembke W, Zha W, Batey S, Bertschinger J, et al.
J Biol Chem
. 2014 Apr;
289(20):14392-8.
PMID: 24692552
Fynomers are small binding proteins derived from the human Fyn SH3 domain. Using phage display technology, Fynomers were generated inhibiting the activity of the proinflammatory cytokine interleukin-17A (IL-17A). One specific...
5.
Banner D, Gsell B, Benz J, Bertschinger J, Burger D, Brack S, et al.
Acta Crystallogr D Biol Crystallogr
. 2013 May;
69(Pt 6):1124-37.
PMID: 23695257
The aspartic protease BACE2 is responsible for the shedding of the transmembrane protein Tmem27 from the surface of pancreatic β-cells, which leads to inactivation of the β-cell proliferating activity of...
6.
Schlatter D, Brack S, Banner D, Batey S, Benz J, Bertschinger J, et al.
MAbs
. 2012 Jun;
4(4):497-508.
PMID: 22653218
The serine protease chymase (EC = 3.4.21.39) is expressed in the secretory granules of mast cells, which are important in allergic reactions. Fynomers, which are binding proteins derived from the...
7.
8.
Bertschinger J, Grabulovski D, Neri D
Protein Eng Des Sel
. 2007 Jan;
20(2):57-68.
PMID: 17242027
Selection technologies such as phage and ribosome display, which provide a physical linkage between genetic information and encoded polypeptide, are important tools for the engineering of proteins for diagnostic and...
9.
Bertschinger J, Neri D
Protein Eng Des Sel
. 2004 Nov;
17(9):699-707.
PMID: 15522920
We present a novel method for the directed evolution of polypeptides, which combines in vitro compartmentalization and covalent DNA display. A library of linear DNA fragments is co-packaged with an...
10.
Heinis C, Bertschinger J, Neri D
Methods Mol Biol
. 2003 Jun;
230:313-28.
PMID: 12824592
No abstract available.