Julian Adams
Overview
Explore the profile of Julian Adams including associated specialties, affiliations and a list of published articles.
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Articles
63
Citations
7152
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0
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Recent Articles
1.
Galindo-Trigo S, Khandare V, Roosjen M, Adams J, Wangler A, Bayer M, et al.
Curr Biol
. 2024 Jun;
34(13):3020-3030.e7.
PMID: 38917797
Plants have evolved mechanisms to abscise organs as they develop or when exposed to unfavorable conditions. Uncontrolled abscission of petals, fruits, or leaves can impair agricultural productivity. Despite its importance...
2.
Phetluan W, Wanchana S, Aesomnuk W, Adams J, Pitaloka M, Ruanjaichon V, et al.
Plant Sci
. 2023 Feb;
330:111624.
PMID: 36737006
Stomata regulate photosynthesis and water loss. They have been an active subject of research for centuries, but our knowledge of the genetic components that regulate stomatal development in crops remains...
3.
Rahaman M, Lam F, Zhong L, Teo T, Adams J, Yu M, et al.
Mol Oncol
. 2019 Aug;
13(10):2178-2193.
PMID: 31398271
Colorectal cancer (CRC) remains one of the most lethal human malignancies, and pursuit of new therapeutic targets for treatment has been a major research focus. Cyclin-dependent kinase 9 (CDK9), which...
4.
Zadra G, Ribeiro C, Chetta P, Ho Y, Cacciatore S, Gao X, et al.
Proc Natl Acad Sci U S A
. 2018 Dec;
116(2):631-640.
PMID: 30578319
A hallmark of prostate cancer progression is dysregulation of lipid metabolism via overexpression of fatty acid synthase (FASN), a key enzyme in de novo fatty acid synthesis. Metastatic castration-resistant prostate...
5.
CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia
Rahaman M, Yu Y, Zhong L, Adams J, Lam F, Li P, et al.
Invest New Drugs
. 2018 Sep;
37(4):625-635.
PMID: 30194564
Acute myeloid leukemia (AML) is the most common form of acute leukemia with dismal long-term prognosis with age. The most aggressive subtype of AML is MLL-AML that is characterized by...
6.
Modi R, Adams J
Evolution
. 2017 Jun;
45(3):656-667.
PMID: 28568831
Evolutionary changes are described in plasmid-containing strains isolated after approximately 800 generations of growth in glucose-limited chemostat culture. The reproductive fitness increased dramatically over this period. Genetic changes associated with...
7.
Levin J, Holtzman S, Maraganore J, Hastings P, Cohen R, Dahiyat B, et al.
Nat Biotechnol
. 2017 Mar;
35(3):204-206.
PMID: 28267733
No abstract available.
8.
De Henau O, Rausch M, Winkler D, Campesato L, Liu C, Cymerman D, et al.
Nature
. 2016 Nov;
539(7629):443-447.
PMID: 27828943
Recent clinical trials using immunotherapy have demonstrated its potential to control cancer by disinhibiting the immune system. Immune checkpoint blocking (ICB) antibodies against cytotoxic-T-lymphocyte-associated protein 4 or programmed cell death...
9.
Li P, Diab S, Yu M, Adams J, Islam S, Basnet S, et al.
Oncotarget
. 2016 Jul;
7(35):56811-56825.
PMID: 27462781
Cytarabine (Ara-C) is a first line clinical therapeutic agent for treatment of acute myeloid leukemia (AML). However, this therapy is limited due to high rate of resistance and relapse. Recent...
10.
Adams J, Rosenzweig F
Genomics
. 2014 Oct;
104(6 Pt A):393-8.
PMID: 25315137
We chronicle and dissect the history of the field of Experimental Microbial Evolution, beginning with work by Monod. Early research was largely carried out by microbiologists and biochemists, who used...