Julia Yue Cui
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Explore the profile of Julia Yue Cui including associated specialties, affiliations and a list of published articles.
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75
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1828
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Recent Articles
11.
Dutta M, Weigel K, Patten K, Valenzuela A, Wallis C, Bein K, et al.
Toxicol Rep
. 2022 Mar;
9:432-444.
PMID: 35310146
Background: Traffic-related air pollution (TRAP) is linked to increased risk for age-related dementia, including Alzheimer's disease (AD). The gut microbiome is posited to influence AD risk, and an increase in...
12.
Little M, Dutta M, Li H, Matson A, Shi X, Mascarinas G, et al.
Acta Pharm Sin B
. 2022 Mar;
12(2):801-820.
PMID: 35256948
Pharmacological activation of the xenobiotic-sensing nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) is well-known to increase drug metabolism and reduce inflammation. Little is known regarding their...
13.
Zhang A, Matsushita M, Zhang L, Wang H, Shi X, Gu H, et al.
Commun Biol
. 2021 Dec;
4(1):1398.
PMID: 34912029
The human Apolipoprotein E4 (ApoE4) variant is the strongest known genetic risk factor for Alzheimer's disease (AD). Cadmium (Cd) has been shown to impair learning and memory at a greater...
14.
Dutta M, Lim J, Cui J
Drug Metab Dispos
. 2021 Dec;
50(4):478-491.
PMID: 34862253
It is well-known that the pregnane X receptor (PXR)/Nr1i2 is a critical xenobiotic-sensing nuclear receptor enriched in liver and intestine and is responsible for drug-drug interactions, due to its versatile...
15.
Lim J, Suh Y, Faustman E, Cui J
Drug Metab Dispos
. 2021 Dec;
50(10):1396-1413.
PMID: 34857530
Perfluorinated carboxylic acids (PFCAs) are widespread environmental pollutants for which human exposure has been documented. PFCAs at high doses are known to regulate xenobiotic transporters partly through peroxisome proliferator-activated receptor...
16.
Ioannou G, Lee S, Linsley P, Gersuk V, Yeh M, Chen Y, et al.
Hepatol Commun
. 2021 Nov;
6(4):780-794.
PMID: 34816633
Proprotein convertase subtilisin/kexin type 9 (Pcsk9) binds to hepatic low-density lipoprotein receptor (LDLR) and induces its internalization and degradation. Pcsk9 inhibition increases LDLR expression by hepatocytes, which causes increased uptake...
17.
Fu Z, Selwyn F, Cui J, Klaassen C
Toxicol Appl Pharmacol
. 2021 Oct;
433:115775.
PMID: 34715074
To identify host responses induced by commensal microbiota in intestine, transcriptomes of four sections of the intestine were compared between germ-free (GF) mice and conventional (CV) controls using RNA-Seq. Cuffdiff...
18.
Lim J, Dutta M, Dempsey J, Lehmler H, MacDonald J, Bammler T, et al.
Toxicol Sci
. 2021 Aug;
184(1):83-103.
PMID: 34453844
Recent evidence suggests that complex diseases can result from early life exposure to environmental toxicants. Polybrominated diphenyl ethers (PBDEs), and polychlorinated biphenyls (PCBs) are persistent organic pollutants (POPs) and remain...
19.
Kim S, Choi S, Dutta M, Asubonteng J, Polunas M, Goedken M, et al.
Biochem Pharmacol
. 2021 Jul;
193:114698.
PMID: 34303710
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease due to the current epidemics of obesity and diabetes. The pregnane X receptor (PXR) is a xenobiotic-sensing nuclear...
20.
Li N, Koester S, Lachance D, Dutta M, Cui J, Dey N
iScience
. 2021 Jun;
24(6):102508.
PMID: 34142026
Gut motility is regulated by the microbiome via mechanisms that include bile acid metabolism. To localize the effects of microbiome-generated bile acids, we colonized gnotobiotic mice with different synthetic gut...